N-benzyloxycarbonylglycine hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a N-benzyloxycarbonylglycine hydrolase (EC 3.5.1.58) is an enzyme that catalyzes the chemical reaction

N-benzyloxycarbonylglycine + H₂O benzyl alcohol + CO₂ + glycine

Thus, the two substrates of this enzyme are N-benzyloxycarbonylglycine and H₂O, whereas its 3 products are benzyl alcohol, CO₂, and glycine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-benzyloxycarbonylglycine urethanehydrolase. Other names in common use include benzyloxycarbonylglycine hydrolase, Nalpha-carbobenzoxyamino acid amidohydrolase, Nalpha-benzyloxycarbonyl amino acid urethane hydrolase, and Nalpha-benzyloxycarbonyl amino acid urethane hydrolase I. It has 2 cofactors: zinc, and Cobalt.

[edit] References

• IUBMB entry for 3.5.1.58
• BRENDA references for 3.5.1.58 (Recommended.)
• PubMed references for 3.5.1.58
• PubMed Central references for 3.5.1.58
• Google Scholar references for 3.5.1.58
• characterization of a novel enzyme N (1985). "alpha-benzyloxycarbonyl amino acid urethane hydrolase, from Streptococcus faecalis R ATCC 8043". Agric. Biol. Chem. 49: 967–972. 

[edit] External links

The CAS registry number for this enzyme class is 91930-69-7.

• IUBMB entry for 3.5.1.58

• KEGG entry for 3.5.1.58

• BRENDA entry for 3.5.1.58

• NiceZyme view of 3.5.1.58

• EC2PDB: PDB structures for 3.5.1.58

• PRIAM entry for 3.5.1.58

• PUMA2 entry for 3.5.1.58

• IntEnz: Integrated Enzyme entry for 3.5.1.58

• MetaCyc entry for 3.5.1.58

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050125: N-benzyloxycarbonylglycine hydrolase

• AMIGO entry for GO code 0050125: N-benzyloxycarbonylglycine hydrolase