N-acetylglucosamine deacetylase

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In enzymology, a N-acetylglucosamine deacetylase (EC 3.5.1.33) is an enzyme that catalyzes the chemical reaction

N-acetyl-D-glucosamine + H2O \rightleftharpoons D-glucosamine + acetate

Thus, the two substrates of this enzyme are N-acetyl-D-glucosamine and H2O, whereas its two products are D-glucosamine and acetate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-acetyl-D-glucosamine amidohydrolase. Other names in common use include acetylaminodeoxyglucose acetylhydrolase, and N-acetyl-D-glucosaminyl N-deacetylase. This enzyme participates in aminosugars metabolism.

Contents

[edit] Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2C1G and 2C1I.

[edit] References

[edit] External links

The CAS registry number for this enzyme class is 9012-32-2.

[edit] Gene Ontology (GO) codes