N-Acetylneuraminic acid
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N-Acetylneuraminic acid | |
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Identifiers | |
CAS number | [131-48-6] |
PubChem | |
MeSH | |
Properties | |
Molecular formula | C11H19NO9 |
Molar mass | 309.273 |
Appearance | White crystalline powder |
Melting point |
186°C (decomposes) |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
N-Acetylneuraminic acid (Neu5Ac or NANA) is the predominant sialic acid.
The negative charge of this chemical is responsible for the slippery feel of saliva and mucins coating the body’s organs.
Despite its role of acting as "decoy" for invading pathogens, Neu5Ac is becoming known as an agent necessary for mediating ganglioside distribution and structures in the brain.
Along with involvement in preventing infections (mucus associated with mucous membranes - mouth, nose, GI, respiratory tract), Neu5Ac acts as a receptor for influenza viruses to allow attachment to mucous cells (an early step in contracting the flu).
[edit] See also
- Neuraminic acid
- Sialic acid
- N-Glycolylneuraminic acid