MYOZ1

From Wikipedia, the free encyclopedia

Myozenin 1

Identifiers

MYOZ1; CS-2; FATZ; MYOZ

External IDs

OMIM: 605603 MGI: 1929471 HomoloGene: 23311

Gene ontology
Molecular Function:	• structural molecule activity • protein binding • FATZ binding
Cellular Component:	• nucleus • actin cytoskeleton
Biological Process:	• myofibril assembly

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_021245 (mRNA)
NP_067068 (protein)

NM_021508 (mRNA)
NP_067483 (protein)

Location

Chr 10: 75.06 - 75.07 Mb

Chr 14: 19.44 - 19.45 Mb

Pubmed search

[1]

[2]

Myozenin 1, also known as MYOZ1, is a human gene.^[1]

[edit] References

^ Entrez Gene: MYOZ1 myozenin 1.

[edit] Further reading

Faulkner G, Pallavicini A, Formentin E, et al. (1999). "ZASP: a new Z-band alternatively spliced PDZ-motif protein.". J. Cell Biol. 146 (2): 465–75. PMID 10427098.
Faulkner G, Pallavicini A, Comelli A, et al. (2001). "FATZ, a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle.". J. Biol. Chem. 275 (52): 41234–42. doi:10.1074/jbc.M007493200. PMID 10984498.
Frey N, Richardson JA, Olson EN (2001). "Calsarcins, a novel family of sarcomeric calcineurin-binding proteins.". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14632–7. doi:10.1073/pnas.260501097. PMID 11114196.
Takada F, Vander Woude DL, Tong HQ, et al. (2001). "Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines.". Proc. Natl. Acad. Sci. U.S.A. 98 (4): 1595–600. doi:10.1073/pnas.041609698. PMID 11171996.
Frey N, Olson EN (2002). "Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins.". J. Biol. Chem. 277 (16): 13998–4004. doi:10.1074/jbc.M200712200. PMID 11842093.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Gontier Y, Taivainen A, Fontao L, et al. (2006). "The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.". J. Cell. Sci. 118 (Pt 16): 3739–49. doi:10.1242/jcs.02484. PMID 16076904.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Arola AM, Sanchez X, Murphy RT, et al. (2007). "Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy.". Mol. Genet. Metab. 90 (4): 435–40. doi:10.1016/j.ymgme.2006.12.008. PMID 17254821.
Posch MG, Perrot A, Dietz R, et al. (2007). "Mutations in MYOZ1 as well as MYOZ2 encoding the calsarcins are not associated with idiopathic and familial dilated cardiomyopathy.". Mol. Genet. Metab. 91 (2): 207–8. doi:10.1016/j.ymgme.2007.02.014. PMID 17434779.