MYO10

From Wikipedia, the free encyclopedia

Myosin X

Identifiers

MYO10; FLJ10639; FLJ21066; FLJ22268; FLJ43256; KIAA0799; MGC131988

External IDs

OMIM: 601481 MGI: 107716 HomoloGene: 36328

Gene ontology
Molecular Function:	• nucleotide binding • motor activity • actin binding • ATP binding
Cellular Component:	• cytoskeleton • myosin complex
Biological Process:	• signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_012334 (mRNA)
NP_036466 (protein)

XM_001006806 (mRNA)
XP_001006806 (protein)

Location

Chr 5: 16.72 - 16.99 Mb

Chr 15: 25.57 - 25.76 Mb

Pubmed search

[1]

[2]

Myosin X, also known as MYO10, is a human gene.^[1]

[edit] References

^ Entrez Gene: MYO10 myosin X.

[edit] Further reading

Hasson T, Skowron JF, Gilbert DJ, et al. (1997). "Mapping of unconventional myosins in mouse and human.". Genomics 36 (3): 431-9. doi:10.1006/geno.1996.0488. PMID 8884266.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (5): 277-86. PMID 9872452.
Rojas K, Serrano de la Peña L, Gallardo T, et al. (2000). "Physical map and characterization of transcripts in the candidate interval for familial chondrocalcinosis at chromosome 5p15.1.". Genomics 62 (2): 177-83. doi:10.1006/geno.1999.5997. PMID 10610710.
Berg JS, Derfler BH, Pennisi CM, et al. (2000). "Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin.". J. Cell. Sci. 113 Pt 19: 3439-51. PMID 10984435.
Rogers MS, Strehler EE (2001). "The tumor-sensitive calmodulin-like protein is a specific light chain of human unconventional myosin X.". J. Biol. Chem. 276 (15): 12182-9. doi:10.1074/jbc.M010056200. PMID 11278607.
Cox D, Berg JS, Cammer M, et al. (2002). "Myosin X is a downstream effector of PI(3)K during phagocytosis.". Nat. Cell Biol. 4 (7): 469-77. doi:10.1038/ncb805. PMID 12055636.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Navarro-Lérida I, Martínez Moreno M, Roncal F, et al. (2004). "Proteomic identification of brain proteins that interact with dynein light chain LC8.". Proteomics 4 (2): 339-46. doi:10.1002/pmic.200300528. PMID 14760703.
Zhang H, Berg JS, Li Z, et al. (2004). "Myosin-X provides a motor-based link between integrins and the cytoskeleton.". Nat. Cell Biol. 6 (6): 523-31. doi:10.1038/ncb1136. PMID 15156152.
Tokuo H, Ikebe M (2004). "Myosin X transports Mena/VASP to the tip of filopodia.". Biochem. Biophys. Res. Commun. 319 (1): 214-20. doi:10.1016/j.bbrc.2004.04.167. PMID 15158464.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55-65. doi:10.1101/gr.4039406. PMID 16344560.
Sousa AD, Berg JS, Robertson BW, et al. (2006). "Myo10 in brain: developmental regulation, identification of a headless isoform and dynamics in neurons.". J. Cell. Sci. 119 (Pt 1): 184-94. doi:10.1242/jcs.02726. PMID 16371656.
Bohil AB, Robertson BW, Cheney RE (2006). "Myosin-X is a molecular motor that functions in filopodia formation.". Proc. Natl. Acad. Sci. U.S.A. 103 (33): 12411-6. doi:10.1073/pnas.0602443103. PMID 16894163.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.