MYL7

From Wikipedia, the free encyclopedia

Myosin, light chain 7, regulatory

Identifiers

MYL7; MYL2A; MYLC2A

External IDs

Gene ontology
Molecular Function:	• microfilament motor activity • calcium ion binding • ATPase activity, coupled
Cellular Component:	• myosin complex
Biological Process:	• smooth muscle contraction • actin filament-based movement

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_021223 (mRNA)
NP_067046 (protein)

NM_022879 (mRNA)
NP_075017 (protein)

Location

Chr 7: 44.14 - 44.15 Mb

Chr 11: 5.8 - 5.8 Mb

Pubmed search

[1]

[2]

Myosin, light chain 7, regulatory, also known as MYL7, is a human gene.^[1]

[edit] References

^ Entrez Gene: MYL7 myosin, light chain 7, regulatory.

[edit] Further reading

Ching YH, Ghosh TK, Cross SJ, et al. (2005). "Mutation in myosin heavy chain 6 causes atrial septal defect.". Nat. Genet. 37 (4): 423-8. doi:10.1038/ng1526. PMID 15735645.
Grimm M, Haas P, Willipinski-Stapelfeldt B, et al. (2005). "Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the alpha 1-adrenergic positive inotropic effect in human atrium.". Cardiovasc. Res. 65 (1): 211-20. doi:10.1016/j.cardiores.2004.09.019. PMID 15621049.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Kovács M, Wang F, Hu A, et al. (2003). "Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform.". J. Biol. Chem. 278 (40): 38132-40. doi:10.1074/jbc.M305453200. PMID 12847096.
Bird SD, Doevendans PA, van Rooijen MA, et al. (2003). "The human adult cardiomyocyte phenotype.". Cardiovasc. Res. 58 (2): 423-34. PMID 12757876.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Nishigaki R, Shinohara T, Toda T, et al. (2002). "An extra human chromosome 21 reduces mlc-2a expression in chimeric mice and Down syndrome.". Biochem. Biophys. Res. Commun. 295 (1): 112-8. PMID 12083776.
Kubalak SW, Miller-Hance WC, O'Brien TX, et al. (1994). "Chamber specification of atrial myosin light chain-2 expression precedes septation during murine cardiogenesis.". J. Biol. Chem. 269 (24): 16961-70. PMID 8207020.
Hailstones D, Barton P, Chan-Thomas P, et al. (1992). "Differential regulation of the atrial isoforms of the myosin light chains during striated muscle development.". J. Biol. Chem. 267 (32): 23295-300. PMID 1429676.