Mycobacterium wolinskyi

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Mycobacterium wolinskyi

Kingdom:	Bacteria
Phylum:	Actinobacteria
Order:	Actinomycetales
Suborder:	Corynebacterineae
Family:	Mycobacteriaceae
Genus:	Mycobacterium
Species:	M. wolinskyi

Binomial name

Mycobacterium wolinskyi
Brown et al. 1999, ATCC 700010

Mycobacterium wolinskyi is a rapidly growing mycobacterium most commonly seen in post-traumatic wound infections, especially those following open fractures and with associated osteomyelitis. Mycobacterium wolinskyi is clearly clinically significant, and occur in the same settings as Mycobacterium smegmatis and members of the Mycobacterium fortuitum complex, they differ from members of the Mycobacterium fortuitum complex in the type of chronic lung disease they produce, with essentially all cases occurring in the setting of chronic lipoid pneumonia, either secondary to chronic oil ingestion or chronic aspiration (usually achalasia). Etymology: Wolinsky, named after Emanuel Wolinsky in honour of, and in recognition for, significant contributions to the study of the non-tuberculous mycobacteria.

Mycobacterium wolinskyi was previously known as Mycobacterium smegmatis group 3.

1 Description
2 Pathogenesis
3 Type Strain
4 References

[edit] Description

Microscopy

Gram-positive, nonmotile and acid-fast rods.

Colony characteristics

Smooth to mucoid, off-white to cream coloured and nonpigmented colonies.
Visible growth in 2 to 4 days on Middlebrook 7H10 agar.

Physiology

No pigment is produced and growth occurs at 30, 35 and 45 °C.
Isolates grow on MacConkey agar without crystal violet and in the presence of 5% NaCl, are negative for arylsulfatase activity at 3 days.
Positive for iron uptake and nitrate reductase.
They produce low-level semi-quantitative catalase activity that is stable at 68 °C, pH 7±0.
The type strain is susceptible to amikacin and sulfamethoxazole, intermediately susceptible to doxycycline and ciprofoxacin, variably susceptible to cefmetazole, cefoxitin, chloramphenicol and clarithromycin, and resistant to isoniazid, rifampin and tobramycin.

[edit] Pathogenesis

M. wolinskyi causes human disease and is most commonly seen in post-traumatic wound infections, especially those following open fractures and with associated osteomyelitis

[edit] Type Strain

The type strain, ATCC 700010T (MO739), was recovered from a post-surgical facial abscess in Switzerland.
Strain MO739 = ATCC 700010 = CCUG 47168 = CIP 106348 = DSM 44493 = JCM 13393.

[edit] References

Brown B.A., 1999. Mycobacterium wolinskyi sp. nov. and Mycobacterium goodii sp. nov., two new rapidly growing species related to Mycobacterium smegmatis and associated with human wound infections: a cooperative study from the International Working Group on Mycobacterial Taxonomy. Int. J. Syst. Bacteriol., 49, 1493-1511.