Mycobacterium goodii

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Mycobacterium goodii

Scientific classification

Kingdom:	Bacteria
Phylum:	Actinobacteria
Order:	Actinomycetales
Suborder:	Corynebacterineae
Family:	Mycobacteriaceae
Genus:	Mycobacterium
Species:	M. goodii

Binomial name

Mycobacterium goodii
Brown et al. 1999, ATCC 700504

Mycobacterium goodii

1 Description
2 Pathogenesis
3 Type Strain
4 References

[edit] Description

Gram-positive, nonmotile and acid-fast rods.

Colony characteristics

Smooth to mucoid, off-white to cream coloured colonies. Yellow to orange pigment produced in 78% of all strains, after 10-14 days incubation.

Physiology

Rapid growth on Middlebrook 7H10 and trypticase soy agar at 30°C, 35°C and 45°C within 2-4 days.
Susceptible to amikacin, ethambutol, sulfamethoxazole.
Intermediate susceptible to ciprofloxacin, doxycycline and tobramycin.
Variable susceptible to cefmetazole, cefoxitin and clarithromycin.
Resistant to isoniazid and rifampicin.

Differential characteristics

Comparable clinical settings to M. smegmatis and members of the M. fortuitum complex.

[edit] Pathogenesis

Production of post-traumatic wound infections especially those following open fractures and with associated osteomyelitis and chronic lipoid pneumonia.

[edit] Type Strain

First isolated from a patient with a post-traumatic osteomyelitis of the heel(USA). Strain MO69 = ATCC 700504 = CIP 106349 = DSM 44492 = JCM 12689. Mycobacterium goodii was previously known as Mycobacterium smegmatis group 2.

[edit] References

Brown et al. 1999. Mycobacterium wolinskyi sp. nov. and Mycobacterium goodii sp. nov., two new rapidly growing species related to Mycobacterium smegmatis and associated with human wound infections: a cooperative study from the International Working Group on Mycobacterial Taxonomy. Int. J. Syst. Bacteriol., 1999, 49, 1493-1511.