MYCBP2

From Wikipedia, the free encyclopedia

MYC binding protein 2

Identifiers

MYCBP2; PAM; DKFZp686M08244; FLJ10106; FLJ13826; FLJ21597; FLJ21646; KIAA0916

External IDs

OMIM: 610392 MGI: 2179432 HomoloGene: 9005

Gene ontology
Molecular Function:	• protein binding • zinc ion binding • ligase activity • protein homodimerization activity • metal ion binding
Cellular Component:	• nucleus
Biological Process:	• transcription • regulation of transcription, DNA-dependent • ubiquitin cycle

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_015057 (mRNA)
NP_055872 (protein)

NM_207215 (mRNA)
NP_997098 (protein)

Location

Chr 13: 76.52 - 76.8 Mb

Chr 14: 102 - 102.23 Mb

Pubmed search

[1]

[2]

MYC binding protein 2, also known as MYCBP2, is a human gene.^[1]

[edit] References

^ Entrez Gene: MYCBP2 MYC binding protein 2.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. PMID 12168954.
Guo Q, Xie J, Dang CV, et al. (1998). "Identification of a large Myc-binding protein that contains RCC1-like repeats.". Proc. Natl. Acad. Sci. U.S.A. 95 (16): 9172–7. PMID 9689053.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (6): 355–64. PMID 10048485.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. PMID 11042152.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Murthy V, Han S, Beauchamp RL, et al. (2004). "Pam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complex.". J. Biol. Chem. 279 (2): 1351–8. doi:10.1074/jbc.M310208200. PMID 14559897.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
Pierre SC, Häusler J, Birod K, et al. (2005). "PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate.". EMBO J. 23 (15): 3031–40. doi:10.1038/sj.emboj.7600321. PMID 15257286.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
Gao X, Patel TB (2005). "Histidine residues 912 and 913 in protein associated with Myc are necessary for the inhibition of adenylyl cyclase activity.". Mol. Pharmacol. 67 (1): 42–9. doi:10.1124/mol.104.005355. PMID 15470080.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Benzinger A, Muster N, Koch HB, et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.". Mol. Cell Proteomics 4 (6): 785–95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.