MYBBP1A

From Wikipedia, the free encyclopedia

MYB binding protein (P160) 1a

Identifiers

MYBBP1A; PAP2; FLJ37886; P160

External IDs

OMIM: 604885 MGI: 106181 HomoloGene: 40954

Gene ontology
Molecular Function:	• DNA binding • DNA-directed DNA polymerase activity • transcription factor binding
Cellular Component:	• nucleus • nucleolus • cytoplasm • NLS-dependent protein nuclear import complex
Biological Process:	• transcription • regulation of transcription, DNA-dependent • nucleocytoplasmic transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014520 (mRNA)
NP_055335 (protein)

NM_016776 (mRNA)
NP_058056 (protein)

Location

Chr 17: 4.39 - 4.41 Mb

Chr 11: 72.26 - 72.27 Mb

Pubmed search

[1]

[2]

MYB binding protein (P160) 1a, also known as MYBBP1A, is a human gene.^[1]

[edit] References

^ Entrez Gene: MYBBP1A MYB binding protein (P160) 1a.

[edit] Further reading

Favier D, Gonda TJ (1994). "Detection of proteins that bind to the leucine zipper motif of c-Myb.". Oncogene 9 (1): 305–11. PMID 8302594.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548.
Tavner FJ, Simpson R, Tashiro S, et al. (1998). "Molecular cloning reveals that the p160 Myb-binding protein is a novel, predominantly nucleolar protein which may play a role in transactivation by Myb.". Mol. Cell. Biol. 18 (2): 989–1002. PMID 9447996.
Keough R, Woollatt E, Crawford J, et al. (2000). "Molecular cloning and chromosomal mapping of the human homologue of MYB binding protein (P160) 1A (MYBBP1A) to 17p13.3.". Genomics 62 (3): 483–9. doi:10.1006/geno.1999.6035. PMID 10644447.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
He B, Minges JT, Lee LW, Wilson EM (2002). "The FXXLF motif mediates androgen receptor-specific interactions with coregulators.". J. Biol. Chem. 277 (12): 10226–35. doi:10.1074/jbc.M111975200. PMID 11779876.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus.". Curr. Biol. 12 (1): 1–11. PMID 11790298.
Ohta S, Shiomi Y, Sugimoto K, et al. (2002). "A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein.". J. Biol. Chem. 277 (43): 40362–7. doi:10.1074/jbc.M206194200. PMID 12171929.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus.". Mol. Biol. Cell 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMID 12429849.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Brajenovic M, Joberty G, Küster B, et al. (2004). "Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.". J. Biol. Chem. 279 (13): 12804–11. doi:10.1074/jbc.M312171200. PMID 14676191.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Fan M, Rhee J, St-Pierre J, et al. (2004). "Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK.". Genes Dev. 18 (3): 278–89. doi:10.1101/gad.1152204. PMID 14744933.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics.". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMID 16565220.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Owen HR, Elser M, Cheung E, et al. (2007). "MYBBP1a is a novel repressor of NF-kappaB.". J. Mol. Biol. 366 (3): 725–36. doi:10.1016/j.jmb.2006.11.099. PMID 17196614.