MTO1

From Wikipedia, the free encyclopedia

Mitochondrial translation optimization 1 homolog (S. cerevisiae)

Identifiers

MTO1; CGI-02

External IDs

MGI: 1915541 HomoloGene: 5876

Gene ontology
Molecular Function:	• oxidoreductase activity • FAD binding
Cellular Component:	• mitochondrion
Biological Process:	• electron transport • tRNA processing

Orthologs

Human

Mouse

Refseq

NM_012123 (mRNA)
NP_036255 (protein)

NM_026658 (mRNA)
NP_080934 (protein)

Location

Chr 6: 74.23 - 74.27 Mb

Chr 9: 78.23 - 78.26 Mb

Pubmed search

[1]

[2]

Mitochondrial translation optimization 1 homolog (S. cerevisiae), also known as MTO1, is a human gene.^[1]

[edit] References

^ Entrez Gene: MTO1 mitochondrial translation optimization 1 homolog (S. cerevisiae).

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.". Genome Res. 10 (5): 703-13. PMID 10810093.
Li X, Li R, Lin X, Guan MX (2002). "Isolation and characterization of the putative nuclear modifier gene MTO1 involved in the pathogenesis of deafness-associated mitochondrial 12 S rRNA A1555G mutation.". J. Biol. Chem. 277 (30): 27256-64. doi:10.1074/jbc.M203267200. PMID 12011058.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Bykhovskaya Y, Mengesha E, Wang D, et al. (2005). "Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3.". Mol. Genet. Metab. 83 (3): 199-206. doi:10.1016/j.ymgme.2004.07.009. PMID 15542390.
Krull M, Brosius J, Schmitz J (2005). "Alu-SINE exonization: en route to protein-coding function.". Mol. Biol. Evol. 22 (8): 1702-11. doi:10.1093/molbev/msi164. PMID 15901843.