MTDH

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Metadherin
Identifiers
Symbol(s) MTDH; 3D3; AEG-1; AEG1; LYRIC
External IDs OMIM: 610323 MGI: 1914404 HomoloGene: 12089
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 92140 67154
Ensembl ENSG00000147649 ENSMUSG00000022255
Uniprot Q86UE4 Q05CM0
Refseq NM_178812 (mRNA)
NP_848927 (protein)		 NM_026002 (mRNA)
NP_080278 (protein)
Location Chr 8: 98.73 - 98.81 Mb Chr 15: 34.03 - 34.09 Mb
Pubmed search [1] [2]

Metadherin, also known as MTDH, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: MTDH metadherin.

[edit] Further reading

  • Emdad L, Sarkar D, Su ZZ, et al. (2007). "Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration.". Pharmacol. Ther. 114 (2): 155–70. doi:10.1016/j.pharmthera.2007.01.010. PMID 17397930. 
  • van 't Veer LJ, Dai H, van de Vijver MJ, et al. (2002). "Gene expression profiling predicts clinical outcome of breast cancer.". Nature 415 (6871): 530–6. doi:10.1038/415530a. PMID 11823860. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Sutherland HG, Lam YW, Briers S, et al. (2004). "3D3/lyric: a novel transmembrane protein of the endoplasmic reticulum and nuclear envelope, which is also present in the nucleolus.". Exp. Cell Res. 294 (1): 94–105. doi:10.1016/j.yexcr.2003.11.020. PMID 14980505. 
  • Brown DM, Ruoslahti E (2004). "Metadherin, a cell surface protein in breast tumors that mediates lung metastasis.". Cancer Cell 5 (4): 365–74. PMID 15093543. 
  • Britt DE, Yang DF, Yang DQ, et al. (2004). "Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells.". Exp. Cell Res. 300 (1): 134–48. doi:10.1016/j.yexcr.2004.06.026. PMID 15383321. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Kang DC, Su ZZ, Sarkar D, et al. (2005). "Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1.". Gene 353 (1): 8–15. doi:10.1016/j.gene.2005.04.006. PMID 15927426. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Lee SG, Su ZZ, Emdad L, et al. (2007). "Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc.". Proc. Natl. Acad. Sci. U.S.A. 103 (46): 17390–5. doi:10.1073/pnas.0608386103. PMID 17088530. 
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