MTCH1

From Wikipedia, the free encyclopedia

Mitochondrial carrier homolog 1 (C. elegans)

Identifiers

MTCH1; PSAP; CGI-64; MGC131998

External IDs

OMIM: 610449 MGI: 1929261 HomoloGene: 22807

Gene ontology
Molecular Function:	• binding • PDZ domain binding
Cellular Component:	• intracellular • mitochondrion • membrane • integral to membrane
Biological Process:	• transport • apoptosis • caspase activation • regulation of signal transduction • positive regulation of apoptosis • neuronal ion channel clustering

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014341 (mRNA)
NP_055156 (protein)

XM_991703 (mRNA)
XP_996797 (protein)

Location

Chr 6: 37.04 - 37.06 Mb

Chr 17: 29.06 - 29.07 Mb

Pubmed search

[1]

[2]

Mitochondrial carrier homolog 1 (C. elegans), also known as MTCH1, is a human gene.^[1]

[edit] References

^ Entrez Gene: MTCH1 mitochondrial carrier homolog 1 (C. elegans).

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Xu X, Shi Y, Wu X, et al. (2000). "Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1.". J. Biol. Chem. 274 (46): 32543–6. PMID 10551805.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.". Genome Res. 10 (5): 703–13. PMID 10810093.
Xu X, Shi YC, Gao W, et al. (2003). "The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein.". J. Biol. Chem. 277 (50): 48913–22. doi:10.1074/jbc.M209613200. PMID 12377771.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Lamarca V, Sanz-Clemente A, Pérez-Pé R, et al. (2007). "Two isoforms of PSAP/MTCH1 share two proapoptotic domains and multiple internal signals for import into the mitochondrial outer membrane.". Am. J. Physiol., Cell Physiol. 293 (4): C1347–61. doi:10.1152/ajpcell.00431.2006. PMID 17670888.