MT1E

From Wikipedia, the free encyclopedia

Metallothionein 1E

PDB rendering based on 1mhu.

Available structures: 1mhu, 1mrb, 2mhu, 2mrt

Identifiers

Symbol(s)

MT1E; MT1; MTD

External IDs

OMIM: 156351 MGI: 97171 HomoloGene: 81614

Gene ontology
Molecular Function:	• copper ion binding • zinc ion binding • cadmium ion binding • metal ion binding
Cellular Component:	• cytoplasm
Biological Process:	• biological_process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_175617 (mRNA)
NP_783316 (protein)

NM_013602 (mRNA)
NP_038630 (protein)

Location

Chr 16: 55.22 - 55.22 Mb

Chr 8: 97.07 - 97.07 Mb

Pubmed search

[1]

[2]

Metallothionein 1E, also known as MT1E, is a human gene.^[1]

[edit] References

^ Entrez Gene: MT1E metallothionein 1E.

[edit] Further reading

West AK, Stallings R, Hildebrand CE, et al. (1991). "Human metallothionein genes: structure of the functional locus at 16q13.". Genomics 8 (3): 513-8. PMID 2286373.
Schmidt CJ, Jubier MF, Hamer DH (1985). "Structure and expression of two human metallothionein-I isoform genes and a related pseudogene.". J. Biol. Chem. 260 (12): 7731-7. PMID 2581970.
Le Beau MM, Diaz MO, Karin M, Rowley JD (1985). "Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia.". Nature 313 (6004): 709-11. PMID 3856101.
Karin M, Eddy RL, Henry WM, et al. (1984). "Human metallothionein genes are clustered on chromosome 16.". Proc. Natl. Acad. Sci. U.S.A. 81 (17): 5494-8. PMID 6089206.
Carter AD, Felber BK, Walling MJ, et al. (1985). "Duplicated heavy metal control sequences of the mouse metallothionein-I gene.". Proc. Natl. Acad. Sci. U.S.A. 81 (23): 7392-6. PMID 6095291.
Kondo Y, Kuo SM, Lazo JS (1994). "Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum.". J. Pharmacol. Exp. Ther. 270 (3): 1313-8. PMID 7932184.
Pauwels M, van Weyenbergh J, Soumillion A, et al. (1994). "Induction by zinc of specific metallothionein isoforms in human monocytes.". Eur. J. Biochem. 220 (1): 105-10. PMID 8119276.
Vandeghinste N, Proost P, De Ley M (2000). "Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes.". Cell. Mol. Biol. (Noisy-le-grand) 46 (2): 419-33. PMID 10774930.
Nguyen A, Jing Z, Mahoney PS, et al. (2000). "In vivo gene expression profile analysis of metallothionein in renal cell carcinoma.". Cancer Lett. 160 (2): 133-40. PMID 11053642.
Oppermann B, Zhang W, Magabo K, Kantorow M (2001). "Identification and spatial analysis of metallothioneins expressed by the adult human lens.". Invest. Ophthalmol. Vis. Sci. 42 (1): 188-93. PMID 11133866.
Garrett SH, Belcastro M, Sens MA, et al. (2001). "Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells.". J. Toxicol. Environ. Health Part A 64 (4): 343-55. PMID 11693492.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages.". Nat. Med. 9 (2): 191-7. doi:10.1038/nm822. PMID 12539042.
Hawse JR, Cumming JR, Oppermann B, et al. (2003). "Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses.". Invest. Ophthalmol. Vis. Sci. 44 (2): 672-9. PMID 12556398.
Sens D, Rossi M, Park S, et al. (2003). "Metallothionein isoform 1 and 2 gene expression in a human urothelial cell line (UROtsa) exposed to CdCl2 and NaAsO2.". J. Toxicol. Environ. Health Part A 66 (21): 2031-46. PMID 14555400.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Sun NN, Fastje CD, Wong SS, et al. (2005). "Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line.". Toxicology and industrial health 19 (7-10): 157-63. PMID 15747776.
Lederer CW, Torrisi A, Pantelidou M, et al. (2007). "Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis.". BMC Genomics 8: 26. doi:10.1186/1471-2164-8-26. PMID 17244347.