MSRB2

From Wikipedia, the free encyclopedia

Methionine sulfoxide reductase B2

Identifiers

MSRB2; CBS-1; CBS1; CGI-131; MGC26104; MSRB; PILB

External IDs

MGI: 1923717 HomoloGene: 56555

Gene ontology
Molecular Function:	• protein-methionine-R-oxide reductase activity • transcription factor activity • protein-methionine-S-oxide reductase activity • zinc ion binding • oxidoreductase activity
Cellular Component:	• mitochondrion
Biological Process:	• protein repair

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_012228 (mRNA)
NP_036360 (protein)

NM_029619 (mRNA)
NP_083895 (protein)

Location

Chr 10: 23.42 - 23.45 Mb

Chr 2: 19.29 - 19.31 Mb

Pubmed search

[1]

[2]

Methionine sulfoxide reductase B2, also known as MSRB2, is a human gene.^[1]

[edit] References

^ Entrez Gene: MSRB2 methionine sulfoxide reductase B2.

[edit] Further reading

Escribano J, Ortego J, Coca-Prados M (1997). "Isolation and characterization of cell-specific cDNA clones from a subtractive library of the ocular ciliary body of a single normal human donor: transcription and synthesis of plasma proteins.". J. Biochem. 118 (5): 921–31. PMID 8749308.
Huang W, Escribano J, Sarfarazi M, Coca-Prados M (1999). "Identification, expression and chromosome localization of a human gene encoding a novel protein with similarity to the pilB family of transcriptional factors (pilin) and to bacterial peptide methionine sulfoxide reductases.". Gene 233 (1-2): 233–40. PMID 10375640.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.". Genome Res. 10 (5): 703–13. PMID 10810093.
Jung S, Hansel A, Kasperczyk H, et al. (2002). "Activity, tissue distribution and site-directed mutagenesis of a human peptide methionine sulfoxide reductase of type B: hCBS1.". FEBS Lett. 527 (1-3): 91–4. PMID 12220640.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Kim HY, Gladyshev VN (2004). "Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases.". Mol. Biol. Cell 15 (3): 1055–64. doi:10.1091/mbc.E03-08-0629. PMID 14699060.
Picot CR, Perichon M, Cintrat JC, et al. (2004). "The peptide methionine sulfoxide reductases, MsrA and MsrB (hCBS-1), are downregulated during replicative senescence of human WI-38 fibroblasts.". FEBS Lett. 558 (1-3): 74–8. doi:10.1016/S0014-5793(03)01530-8. PMID 14759519.
Hansel A, Jung S, Hoshi T, Heinemann SH (2004). "A second human methionine sulfoxide reductase (hMSRB2) reducing methionine-R-sulfoxide displays a tissue expression pattern distinct from hMSRB1.". Redox Rep. 8 (6): 384–8. doi:10.1179/135100003225003429. PMID 14980072.
Schallreuter KU, Rübsam K, Chavan B, et al. (2006). "Functioning methionine sulfoxide reductases A and B are present in human epidermal melanocytes in the cytosol and in the nucleus.". Biochem. Biophys. Res. Commun. 342 (1): 145–52. doi:10.1016/j.bbrc.2006.01.124. PMID 16480945.