MspA porin
From Wikipedia, the free encyclopedia
MspA | ||
---|---|---|
Identifiers | ||
Symbol | MspA | |
Pfam | PF09203 | |
InterPro | IPR015286 | |
SCOP | 1uun | |
OPM family | 35 | |
OPM protein | 1uun | |
Available PDB structures:
1uunB:38-210 |
MspA porin is a membrane porin produced by Mycobacteria, allowing hydrophilic nutrients to enter the bacterium. The protein forms a tightly interconnected octamer with eightfold rotation symmetry that resembles a goblet and contains a central channel. Each subunit fold contains a beta-sandwich of Ig-like topology and a beta-ribbon arm that forms an oligomeric transmembrane barrel[1].
[edit] References
- ^ Schulz GE, Faller M, Niederweis M (2004). "The structure of a mycobacterial outer-membrane channel". Science 303 (5661): -. PMID 14976314.