MOS (gene)

From Wikipedia, the free encyclopedia

V-mos Moloney murine sarcoma viral oncogene homolog

Identifiers

MOS; MGC119962; MGC119963; MSV

External IDs

OMIM: 190060 MGI: 97052 HomoloGene: 3919

Gene ontology
Molecular Function:	• nucleotide binding • protein serine/threonine kinase activity • ATP binding • transferase activity
Biological Process:	• regulation of progression through cell cycle • protein amino acid phosphorylation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_005372 (mRNA)
NP_005363 (protein)

XM_973427 (mRNA)
XP_978521 (protein)

Location

Chr 8: 57.19 - 57.19 Mb

n/a

Pubmed search

[1]

[2]

V-mos Moloney murine sarcoma viral oncogene homolog, also known as MOS, is a human gene.^[1]

[edit] References

^ Entrez Gene: MOS v-mos Moloney murine sarcoma viral oncogene homolog.

[edit] Further reading

Sagata N (1997). "What does Mos do in oocytes and somatic cells?". Bioessays 19 (1): 13–21. doi:10.1002/bies.950190105. PMID 9008413.
Singh B, Arlinghaus RB (1998). "Mos and the cell cycle.". Progress in cell cycle research 3: 251–9. PMID 9552420.
Caubet JF, Mathieu-Mahul D, Bernheim A, et al. (1986). "Human proto-oncogene c-mos maps to 8q11.". EMBO J. 4 (9): 2245–8. PMID 3000766.
Watson R, Oskarsson M, Vande Woude GF (1982). "Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus.". Proc. Natl. Acad. Sci. U.S.A. 79 (13): 4078–82. PMID 6287464.
Heikinheimo O, Lanzendorf SE, Baka SG, Gibbons WE (1995). "Cell cycle genes c-mos and cyclin-B1 are expressed in a specific pattern in human oocytes and preimplantation embryos.". Hum. Reprod. 10 (3): 699–707. PMID 7540181.
Lenormand JL, Benayoun B, Guillier M, et al. (1997). "Mos activates myogenic differentiation by promoting heterodimerization of MyoD and E12 proteins.". Mol. Cell. Biol. 17 (2): 584–93. PMID 9001211.
Liu H, Vuyyuru VB, Pham CD, et al. (1999). "Evidence of an interaction between Mos and Hsp70: a role of the Mos residue serine 3 in mediating Hsp70 association.". Oncogene 18 (23): 3461–70. doi:10.1038/sj.onc.1202699. PMID 10376524.
Pham CD, Vuyyuru VB, Yang Y, et al. (1999). "Evidence for an important role of serine 16 and its phosphorylation in the stabilization of c-Mos.". Oncogene 18 (30): 4287–94. doi:10.1038/sj.onc.1202804. PMID 10439036.
Proikas-Cezanne T, Stabel S, Riethmacher D (2002). "Identification of protein tyrosine phosphatase 1B and casein as substrates for 124-v-Mos.". BMC Biochem. 3: 6. PMID 12022922.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Hassel S, Eichner A, Yakymovych M, et al. (2004). "Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry.". Proteomics 4 (5): 1346–58. doi:10.1002/pmic.200300770. PMID 15188402.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Kalejs M, Ivanov A, Plakhins G, et al. (2006). "Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe.". BMC Cancer 6: 6. doi:10.1186/1471-2407-6-6. PMID 16401344.