Monosaccharide-transporting ATPase

From Wikipedia, the free encyclopedia

In enzymology, a monosaccharide-transporting ATPase (EC 3.6.3.17) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + monosaccharideout ADP + phosphate + monosaccharidein

The 3 substrates of this enzyme are ATP, H₂O, and monosaccharide, whereas its 3 products are ADP, phosphate, and monosaccharide.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (monosaccharide-importing). This enzyme participates in abc transporters - general.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2GX6.

[edit] References

• IUBMB entry for 3.6.3.17
• BRENDA references for 3.6.3.17 (Recommended.)
• PubMed references for 3.6.3.17
• PubMed Central references for 3.6.3.17
• Google Scholar references for 3.6.3.17
• Higgins CF (1992). "ABC transporters: from microorganisms to man". Annu. Rev. Cell. Biol. 8: 67–113. doi:10.1146/annurev.cb.08.110192.000435. PMID 1282354. 
• Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146: 271–8. PMID 7569321. 
• Kemner JM, Liang X, Nester EW (1997). "The Agrobacterium tumefaciens virulence gene chvE is part of a putative ABC-type sugar transport operon". J. Bacteriol. 179: 2452–8. PMID 9079938. 
• Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. PMID 9889977. 
• Song S, Park C (1998). "Utilization of D-ribose through D-xylose transporter". FEMS. Microbiol. Lett. 163: 255–61. PMID 9673030. 
• Griffiths JK and Sansom CE. "The Transporter Factsbook, Academic Press, San Diego, 1998". 

[edit] External links

• IUBMB entry for 3.6.3.17

• KEGG entry for 3.6.3.17

• BRENDA entry for 3.6.3.17

• NiceZyme view of 3.6.3.17

• EC2PDB: PDB structures for 3.6.3.17

• PRIAM entry for 3.6.3.17

• PUMA2 entry for 3.6.3.17

• IntEnz: Integrated Enzyme entry for 3.6.3.17

• MetaCyc entry for 3.6.3.17

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0015407: monosaccharide-transporting ATPase

• AMIGO entry for GO code 0015407: monosaccharide-transporting ATPase