Monoprenyl isoflavone epoxidase

From Wikipedia, the free encyclopedia

In enzymology, a monoprenyl isoflavone epoxidase (EC 1.14.99.34) is an enzyme that catalyzes the chemical reaction

7-O-methylluteone + NADPH + H⁺ + O₂ dihydrofurano derivatives + NADP⁺ + H₂O

The 4 substrates of this enzyme are 7-O-methylluteone, NADPH, H⁺, and O₂, whereas its 3 products are dihydrofurano derivative, NADP⁺, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is 7-O-methylluteone,NADPH:O2 oxidoreductase. Other names in common use include monoprenyl isoflavone monooxygenase, and 7-O-methylluteone:O2 oxidoreductase.

[edit] References

• IUBMB entry for 1.14.99.34
• BRENDA references for 1.14.99.34 (Recommended.)
• PubMed references for 1.14.99.34
• PubMed Central references for 1.14.99.34
• Google Scholar references for 1.14.99.34
• Tanaka M and Tahara S (1997). "FAD-dependent epoxidase as a key enzyme in fungal metabolism of prenylated flavonoids". Phytochemistry 46: 433–439. doi:10.1016/S0031-9422(97)00322-1. 

[edit] External links

• IUBMB entry for 1.14.99.34

• KEGG entry for 1.14.99.34

• BRENDA entry for 1.14.99.34

• NiceZyme view of 1.14.99.34

• EC2PDB: PDB structures for 1.14.99.34

• PRIAM entry for 1.14.99.34

• PUMA2 entry for 1.14.99.34

• IntEnz: Integrated Enzyme entry for 1.14.99.34

• MetaCyc entry for 1.14.99.34

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050602: monoprenyl isoflavone epoxidase

• AMIGO entry for GO code 0050602: monoprenyl isoflavone epoxidase