Molsidomine

From Wikipedia, the free encyclopedia

Molsidomine is an orally active, long acting vasodilating drug. Molsidomine is metabolized in the liver to the active metabolite SIN-1. SIN-1 is an unstable compound that releases nitric oxide upon decay as the actual vasodilating compound.

[edit] Chemistry

Molsidomine as well as SIN-1 are sydnone imines, a class of mesoionic heterocyclic aromatic chemical compounds.

[edit] See also

• Nitric oxide
• Nitric oxide releaser
• Vasodilator

v • d • e Vasodilators used in cardiac diseases (C01D) Nitrates Glyceryl trinitrate • Isosorbide dinitrate • Isosorbide mononitrate • Molsidomine • Pentaerythritol tetranitrate Quinolone vasodilators Flosequinan Others Itramin tosilate • Prenylamine • Oxyfedrine • Benziodarone • Carbocromen • Hexobendine • Etafenone • Heptaminol • Imolamine • Dilazep • Trapidil • Molsidomine • Efloxate • Cinepazet • Cloridarol • Nicorandil • Linsidomine • Nesiritide • Gapicomine