MOBKL3

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Preimplantation protein 3
Identifiers
Symbol(s) PREI3; 2C4D; CGI-95; MGC12264; MOB1; MOB3
External IDs OMIM: 609361 MGI: 104899 HomoloGene: 9116
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 25843 19070
Ensembl ENSG00000115540 ENSMUSG00000025979
Uniprot Q9Y3A3 Q3UGM5
Refseq NM_015387 (mRNA)
NP_056202 (protein)		 NM_025283 (mRNA)
NP_079559 (protein)
Location Chr 2: 198.09 - 198.13 Mb Chr 1: 55.08 - 55.1 Mb
Pubmed search [1] [2]

Preimplantation protein 3, also known as PREI3, is a human gene.[1]

This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed.[1]

[edit] References

  1. ^ a b Entrez Gene: PREI3 preimplantation protein 3.

[edit] Further reading

  • Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.". Genome Res. 10 (5): 703–13. PMID 10810093. 
  • Kawai J, Shinagawa A, Shibata K, et al. (2001). "Functional annotation of a full-length mouse cDNA collection.". Nature 409 (6821): 685–90. doi:10.1038/35055500. PMID 11217851. 
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166. 
  • Moreno CS, Lane WS, Pallas DC (2001). "A mammalian homolog of yeast MOB1 is both a member and a putative substrate of striatin family-protein phosphatase 2A complexes.". J. Biol. Chem. 276 (26): 24253–60. doi:10.1074/jbc.M102398200. PMID 11319234. 
  • Baillat G, Gaillard S, Castets F, Monneron A (2002). "Interactions of phocein with nucleoside-diphosphate kinase, Eps15, and Dynamin I.". J. Biol. Chem. 277 (21): 18961–6. doi:10.1074/jbc.M108818200. PMID 11872741. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
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