MN gene
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The MN blood group in humans is under the control of a pair of co-dominant alleles, LM and LN. Most people in the Eskimo population are M/M, while this genotype is rare among Aborigines. In fact, they tend to possess the opposite genotype (N/N).
The MN blood group system is under the control of an autosomal locus found on chromosome 4 out of 23, with two alleles designated LM and LN. The bloodtype is due to a glycoprotein present on the surface of red blood cells, which behaves as a native antigen. Phenotypic expression at this locus is codominant because an individual may exhibit either one or both antigenic substances. Frequencies of the two alleles vary widely among human populations.
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