MLF1

From Wikipedia, the free encyclopedia


Myeloid leukemia factor 1
Identifiers
Symbol(s) MLF1;
External IDs OMIM: 601402 MGI1341819 HomoloGene7839
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 4291 17349
Ensembl ENSG00000178053 ENSMUSG00000048416
Uniprot P58340 Q3V042
Refseq NM_022443 (mRNA)
NP_071888 (protein)
NM_001039543 (mRNA)
NP_001034632 (protein)
Location Chr 3: 159.77 - 159.81 Mb Chr 3: 67.46 - 67.49 Mb
Pubmed search [1] [2]

Myeloid leukemia factor 1, also known as MLF1, is a human gene.[1]


[edit] References

[edit] Further reading

  • Yoneda-Kato N, Look AT, Kirstein MN, et al. (1996). "The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1.". Oncogene 12 (2): 265-75. PMID 8570204. 
  • Lim R, Winteringham LN, Williams JH, et al. (2002). "MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1.". J. Biol. Chem. 277 (43): 40997-1008. doi:10.1074/jbc.M206041200. PMID 12176995. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Arber DA, Chang KL, Lyda MH, et al. (2003). "Detection of NPM/MLF1 fusion in t(3;5)-positive acute myeloid leukemia and myelodysplasia.". Hum. Pathol. 34 (8): 809-13. PMID 14506644. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Hanissian SH, Akbar U, Teng B, et al. (2004). "cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP.". Oncogene 23 (20): 3700-7. doi:10.1038/sj.onc.1207448. PMID 15116101. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Yoneda-Kato N, Tomoda K, Umehara M, et al. (2005). "Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3.". EMBO J. 24 (9): 1739-49. doi:10.1038/sj.emboj.7600656. PMID 15861129. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 
  • Yoneda-Kato N, Kato JY (2008). "Shuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformation.". Mol. Cell. Biol. 28 (1): 422-34. doi:10.1128/MCB.02335-06. PMID 17967869.