MLF1IP

From Wikipedia, the free encyclopedia

MLF1 interacting protein

Identifiers

MLF1IP; KLIP1; CENP-50; CENP-U; CENP-U(50); CENPU; FLJ23468

External IDs

MGI: 1919126 HomoloGene: 11629

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• chromosome, pericentric region • nucleus • chromosome • cytoplasm
Biological Process:	• transcription • regulation of transcription, DNA-dependent

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_024629 (mRNA)
NP_078905 (protein)

NM_027973 (mRNA)
NP_082249 (protein)

Location

Chr 4: 185.85 - 185.9 Mb

Chr 8: 48.05 - 48.08 Mb

Pubmed search

[1]

[2]

MLF1 interacting protein, also known as MLF1IP, is a human gene.^[1]

[edit] References

^ Entrez Gene: MLF1IP MLF1 interacting protein.

[edit] Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548.
Zhang YJ, Pan HY, Gao SJ (2002). "Reverse transcription slippage over the mRNA secondary structure of the LIP1 gene.". BioTechniques 31 (6): 1286, 1288, 1290, passim. PMID 11768657.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Pan HY, Zhang YJ, Wang XP, et al. (2003). "Identification of a novel cellular transcriptional repressor interacting with the latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus.". J. Virol. 77 (18): 9758-68. PMID 12941884.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Obuse C, Yang H, Nozaki N, et al. (2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.". Genes Cells 9 (2): 105-20. PMID 15009096.
Hanissian SH, Akbar U, Teng B, et al. (2004). "cDNA cloning and characterization of a novel gene encoding the MLF1-interacting protein MLF1IP.". Oncogene 23 (20): 3700-7. doi:10.1038/sj.onc.1207448. PMID 15116101.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Hanissian SH, Teng B, Akbar U, et al. (2005). "Regulation of myeloid leukemia factor-1 interacting protein (MLF1IP) expression in glioblastoma.". Brain Res. 1047 (1): 56-64. doi:10.1016/j.brainres.2005.04.017. PMID 15893739.
Minoshima Y, Hori T, Okada M, et al. (2005). "The constitutive centromere component CENP-50 is required for recovery from spindle damage.". Mol. Cell. Biol. 25 (23): 10315-28. doi:10.1128/MCB.25.23.10315-10328.2005. PMID 16287847.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391-6. doi:10.1073/pnas.0507066103. PMID 16565220.
Foltz DR, Jansen LE, Black BE, et al. (2006). "The human CENP-A centromeric nucleosome-associated complex.". Nat. Cell Biol. 8 (5): 458-69. doi:10.1038/ncb1397. PMID 16622419.
Okada M, Cheeseman IM, Hori T, et al. (2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.". Nat. Cell Biol. 8 (5): 446-57. doi:10.1038/ncb1396. PMID 16622420.
Izuta H, Ikeno M, Suzuki N, et al. (2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.". Genes Cells 11 (6): 673-84. doi:10.1111/j.1365-2443.2006.00969.x. PMID 16716197.
Kang YH, Park JE, Yu LR, et al. (2006). "Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation.". Mol. Cell 24 (3): 409-22. doi:10.1016/j.molcel.2006.10.016. PMID 17081991.
Suzuki H, Arakawa Y, Ito M, et al. (2007). "MLF1-interacting protein is mainly localized in nucleolus through N-terminal bipartite nuclear localization signal.". Anticancer Res. 27 (3B): 1423-30. PMID 17595757.