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Route 21 is a highway in eastern Missouri. Its northern terminus is at Route 30 in Affton. Its southern terminus is at the Arkansas state line (where it continues as Highway 115). In the St. Louis area, it is known as Tesson Ferry Road, which was named after the nineteenth century proprietor of the ferry across the Meramec River.
The section through northern Jefferson County, Missouri was the site of numerous fatal traffic accidents due to the narrow road being unable to handle increased traffic from population growth, and was referred to as "Blood Alley" and "Missouri's Most Dangerous Highway" (and was featured in an Reader's Digest article on dangerous roads)[citation needed]. As a result, the road was rerouted and built to freeway standards; it is currently freeway standard to just north of Hillsboro, Missouri and construction is underway to eventually re-route the road to just south of Hillsboro. Major Towns:Arkansas State Line, Poynor, Hunter, Ellington, Centerville, Lesterville, Arcadia, Ironton, Pilot Knob, Middlebrook Belleview, Graniteville, Junction Connected to:Belgrade, Caledonia, Potosi, Old Mines, Junction Connected to:Richwoods, De Soto, Hillsboro, Otto, Cedar Hill, Concord, Green Park, Lakeshore, Affton, Saint Louis.
Route 30 in Affton
Highway 115 at the Arkansas state line
