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| mir-19 microRNA precursor family |
 |
| Type: |
Gene; miRNA; |
| 2° structure: |
Predicted; PFOLD |
| Seed alignment: |
Griffiths-Jones SR |
| Avg length: |
75.4 nucleotides |
| Avg identity: |
82% |
|
The miR-19 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. Within the human and mouse genome there are three copies of this microRNA that are processed from multiple predicted precursor hairpins:[1][2] [3]
miR-19 has now been predicted or experimentally confirmed in a wide range of vertebrate species (MIPF0000011). In this case the mature sequence is excised from the 3' arm of the hairpin precursor.
[edit] References
- ^ Lagos-Quintana, M; Rauhut R, Lendeckel W, Tuschl T (2001). "Identification of novel genes coding for small expressed RNAs". Science 294: 853–858. doi:10.1126/science.1064921. PMID 11679670.
- ^ Mourelatos, Z; Dostie J, Paushkin S, Sharma A, Charroux B, Abel L, Rappsilber J, Mann M, Dreyfuss G (2002). "miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs". Genes Dev 16: 720–728. doi:10.1101/gad.974702. PMID 11914277.
- ^ Houbaviy, HB; Murray MF, Sharp PA (2003). "Embryonic stem cell-specific MicroRNAs". Dev Cell 5: 351–358. doi:10.1016/S1534-5807(03)00227-2. PMID 12919684.
[edit] External links
