Mir-196 microRNA precursor family

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mir-196 microRNA precursor family

Type:	Gene; miRNA;
2° structure:	Predicted; PFOLD
Seed alignment:	Griffiths-Jones SR
Avg length:	91.1 nucleotides
Avg identity:	73%

miR-196 is a non-coding RNA called a microRNA that has been shown to be expressed in human (MI0000238, MI0000279) and mouse (MI0000552, MI0000553) [1,2]. miR-196 appears to be a vertebrate specific microRNA and has now been predicted or experimentally confirmed in a wide range of vertebrate species (MIPF0000031). In many species the miRNA appears to be expressed from intergenic regions in HOX gene clusters. The hairpin precursors are predicted based on base pairing and cross-species conservation -- their extents are not known. In this case the mature sequence is excised from the 5' arm of the hairpin.

[edit] References

[1] Lagos-Quintana, M; Rauhut R, Meyer J, Borkhardt A, Tuschl T (2003). "New microRNAs from mouse and human". RNA 9: 175–179. doi:10.1261/rna.2146903. PMID 12554859.
[2] Lim, LP; Glasner ME, Yekta S, Burge CB, Bartel DP (2003). "Vertebrate microRNA genes". Science 299: 1540–. doi:10.1126/science.1080372. PMID 12624257.