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| mir-194 microRNA precursor family |
 |
| Type: |
Gene; miRNA; |
| 2° structure: |
Predicted; PFOLD |
| Seed alignment: |
Griffiths-Jones SR |
| Avg length: |
85.0 nucleotides |
| Avg identity: |
79% |
|
In molecular biology, miR-194 microRNA precursor is a small non-coding RNA gene that regulated gene expression. Its expression has been verified in mouse (MI0000236, MI0000733)[1] and in human (MI0000488, MI0000732).[2] mir-194 appears to be a vertebrate-specific miRNA and has now been predicted or experimentally confirmed in a range of vertebrate species (MIPF0000055). The mature microRNA is processed from the longer hairpin precursor by the Dicer enzyme. In this case, the mature sequence is excised from the 5' arm of the hairpin.
[edit] References
- ^ Lagos-Quintana, M; Rauhut R, Meyer J, Borkhardt A, Tuschl T (2003). "New microRNAs from mouse and human". RNA 9: 175–179. doi:10.1261/rna.2146903. PMID 12554859.
- ^ Michael, MZ; O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ (2003). "Reduced accumulation of specific microRNAs in colorectal neoplasia". Mol Cancer Res 1: 882–891. PMID 14573789.
[edit] External links
