Mir-166 microRNA precursor

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mir-166 microRNA precursor

Type:	Gene; miRNA;
2° structure:	Predicted; PFOLD
Seed alignment:	Griffiths-Jones SR, Daub J
Avg length:	123.2 nucleotides
Avg identity:	57%

The plant mir-166 microRNA precursor is a small non-coding RNA gene. This microRNA (miRNA) has now been predicted or experimentally confirmed in a wide range of plant species (MIPF0000004). microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In this case the mature sequence comes from the 3' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences. The mature products are thought to have regulatory roles through complementarity to messenger RNA.

[edit] References

[1] Reinhart, BJ; Weinstein EG, Rhoades MW, Bartel B, Bartel DP (2002). "MicroRNAs in plants". Genes Dev 16: 1616–1626. doi:10.1101/gad.1004402. PMID 12101121.
[2] Ambros, V (2001). "microRNAs: tiny regulators with great potential". Cell 107: 823–826. doi:10.1016/S0092-8674(01)00616-X. PMID 11779458.