MicC RNA

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MicC RNA
Template:Abbreviation
Type: Gene; sRNA;
2° structure: Predicted; PFOLD
Seed alignment: Hershberg R
Avg length: 121.6 nucleotides
Avg identity: 86%

The MicC non-coding RNA (previously known as IS063 [1]) is located between the ompN and ydbK genes in E. coli. This RNA is thought to be a regulator of OmpC expression, with a 5' region of 22 nucleotides potentially forming an antisense interaction with the ompC mRNA. Along with MicF RNA this family may act in conjunction with EnvZ-OmpR two-component system to control the OmpF/OmpC protein ratio in response to a variety of environmental stimuli [2].

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[edit] References

  1. ^ Chen, S; Lesnik EA, Hall TA, Sampath R, Griffey RH, Ecker DJ, Blyn LB (2002). "A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome". Biosystems 65: 157–177. doi:10.1016/S0303-2647(02)00013-8. PMID 12069726. 
  2. ^ Chen, S; Zhang A, Blyn LB, Storz G (2004). "MicC, a second small-RNA regulator of Omp protein expression in Escherichia coli". J Bacteriol 186: 6689–6697. doi:10.1128/JB.186.20.6689-6697.2004. PMID 15466019. 

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