MICAL1

From Wikipedia, the free encyclopedia

Microtubule associated monoxygenase, calponin and LIM domain containing 1

PDB rendering based on 1wyl.

Available structures: 1wyl, 2bra, 2bry, 2c4c, 2co8, 2dk9

Identifiers

Symbol(s)

MICAL1; DKFZp434B1517; FLJ11937; FLJ21739; MICAL; MICAL-1; NICAL

External IDs

OMIM: 607129 MGI: 2385847 HomoloGene: 11246

Gene ontology
Molecular Function:	• monooxygenase activity • protein binding • zinc ion binding • SH3 domain binding • metal ion binding
Cellular Component:	• cytoplasm • cytoskeleton • intermediate filament
Biological Process:	• electron transport • aromatic compound metabolic process • cytoskeleton organization and biogenesis • signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_022765 (mRNA)
NP_073602 (protein)

NM_138315 (mRNA)
NP_612188 (protein)

Location

Chr 6: 109.87 - 109.88 Mb

Chr 10: 41.16 - 41.18 Mb

Pubmed search

[1]

[2]

Microtubule associated monoxygenase, calponin and LIM domain containing 1, also known as MICAL1, is a human gene.^[1]

[edit] References

^ Entrez Gene: MICAL1 microtubule associated monoxygenase, calponin and LIM domain containing 1.

[edit] Further reading

Iwata S, Ohashi Y, Kamiguchi K, Morimoto C (2000). "Beta 1-integrin-mediated cell signaling in T lymphocytes.". J. Dermatol. Sci. 23 (2): 75-86. PMID 10808124.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Hattori A, Okumura K, Nagase T, et al. (2001). "Characterization of long cDNA clones from human adult spleen.". DNA Res. 7 (6): 357-66. PMID 11214971.
Suzuki T, Nakamoto T, Ogawa S, et al. (2002). "MICAL, a novel CasL interacting molecule, associates with vimentin.". J. Biol. Chem. 277 (17): 14933-41. doi:10.1074/jbc.M111842200. PMID 11827972.
Terman JR, Mao T, Pasterkamp RJ, et al. (2002). "MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion.". Cell 109 (7): 887-900. PMID 12110185.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Weide T, Teuber J, Bayer M, Barnekow A (2003). "MICAL-1 isoforms, novel rab1 interacting proteins.". Biochem. Biophys. Res. Commun. 306 (1): 79-86. PMID 12788069.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Fischer J, Weide T, Barnekow A (2005). "The MICAL proteins and rab1: a possible link to the cytoskeleton?". Biochem. Biophys. Res. Commun. 328 (2): 415-23. doi:10.1016/j.bbrc.2004.12.182. PMID 15694364.
Bayer M, Fischer J, Kremerskothen J, et al. (2006). "Identification and characterization of Iporin as a novel interaction partner for rab1.". BMC Cell Biol. 6 (1): 15. doi:10.1186/1471-2121-6-15. PMID 15796781.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Jin X, Zhang J, Dai H, et al. (2007). "Investigation of the four cooperative unfolding units existing in the MICAL-1 CH domain.". Biophys. Chem. 129 (2-3): 269-78. doi:10.1016/j.bpc.2007.06.008. PMID 17662518.