MIB1

From Wikipedia, the free encyclopedia

Mindbomb homolog 1 (Drosophila)

Identifiers

MIB1; DIP-1; DKFZp686I0769; DKFZp761M1710; FLJ90676; MGC129659; MGC129660; MIB; ZZANK2; ZZZ6

External IDs

OMIM: 608677 MGI: 2443157 HomoloGene: 10810

Gene ontology
Molecular Function:	• protein binding • zinc ion binding • ligase activity • metal ion binding
Cellular Component:	• mitochondrion • membrane • cytoplasmic vesicle
Biological Process:	• blood vessel development • in utero embryonic development • somitogenesis • neural tube formation • heart looping • ubiquitin cycle • Notch signaling pathway • heart development • negative regulation of neuron differentiation • positive regulation of endocytosis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_020774 (mRNA)
NP_065825 (protein)

XM_976932 (mRNA)
XP_982026 (protein)

Location

Chr 18: 17.58 - 17.7 Mb

Chr 18: 10.73 - 10.81 Mb

Pubmed search

[1]

[2]

Mindbomb homolog 1 (Drosophila), also known as MIB1, is a human gene.^[1]

[edit] References

^ Entrez Gene: MIB1 mindbomb homolog 1 (Drosophila).

[edit] Further reading

Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (1): 65-73. PMID 10718198.
Wang Z, Tseng CP, Pong RC, et al. (2002). "The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate cancer. Characterization of a novel GTPase-activating protein associated with N-terminal domain of DOC-2/DAB2.". J. Biol. Chem. 277 (15): 12622-31. doi:10.1074/jbc.M110568200. PMID 11812785.
Jin Y, Blue EK, Dixon S, et al. (2003). "A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK.". J. Biol. Chem. 277 (49): 46980-6. doi:10.1074/jbc.M208585200. PMID 12351649.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Itoh M, Kim CH, Palardy G, et al. (2003). "Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta.". Dev. Cell 4 (1): 67-82. PMID 12530964.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Henshall DC, Schindler CK, So NK, et al. (2004). "Death-associated protein kinase expression in human temporal lobe epilepsy.". Ann. Neurol. 55 (4): 485-94. doi:10.1002/ana.20001. PMID 15048887.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Yoo KW, Kim EH, Jung SH, et al. (2006). "Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish.". FEBS Lett. 580 (18): 4409-16. doi:10.1016/j.febslet.2006.07.009. PMID 16857196.
Song R, Koo BK, Yoon KJ, et al. (2007). "Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1.". J. Biol. Chem. 281 (47): 36391-400. doi:10.1074/jbc.M606601200. PMID 17003037.
Zhang L, Nephew KP, Gallagher PJ (2007). "Regulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexes.". J. Biol. Chem. 282 (16): 11795-804. doi:10.1074/jbc.M610430200. PMID 17324930.
Yakut T, Gutenberg A, Bekar A, et al. (2007). "Correlation of chromosomal imbalances by comparative genomic hybridization and expression of EGFR, PTEN, p53, and MIB-1 in diffuse gliomas.". Oncol. Rep. 17 (5): 1037-43. PMID 17390041.
van der Avoort IA, van der Laak JA, Paffen A, et al. (2007). "MIB1 expression in basal cell layer: a diagnostic tool to identify premalignancies of the vulva.". Mod. Pathol. 20 (7): 770-8. doi:10.1038/modpathol.3800796. PMID 17464313.