Mevalonic acid

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Mevalonic acid

IUPAC name	3,5-dihydroxy-3-methylpentanoic acid
Identifiers
CAS number	[150-97-0]
SMILES	C[C@@](O)(CCO)CC(=O)O
Properties
Molecular formula	C₆H₁₂O₄
Molar mass	148.16 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Mevalonic acid is a key organic compound in biochemistry. It is a precursor in the biosynthetic pathway, known as the HMG-CoA reductase pathway, that produces terpenes and steroids.

Mevalonate pathway

Mevalonic acid is very soluble in water and in polar organic solvents. It exists in equilibrium with the lactone, called mevalolactone, formed by internal condensation of its terminal alcohol and carboxylic acid functional groups.

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v • d • e Cholesterol metabolic intermediates

to HMG-CoA	Acetyl-CoA - Acetoacetyl-CoA - HMG-CoA

to Dimethylallyl pyrophosphate	Mevalonic acid - Phosphomevalonic acid - 5-Diphosphomevalonic acid - Isopentenyl pyrophosphate - Dimethylallyl pyrophosphate

Geranyl-	Geranyl pyrophosphate - Geranylgeranyl pyrophosphate

To Cholesterol	Farnesyl pyrophosphate - Squalene - 2,3-Oxidosqualene - Lanosterol

see also enzymes