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The article states that methcathinone releases "radio labled dopamine" from the brain. Shouldn't "radio labled" be removed, as this is just how this effect was dicovered?

You're right. Fixed it. Btw, remember to sign your name. When in the talk page.--Ddhix 2002 08:39, 11 August 2006 (UTC)

Contents 1 Neil 2 Sources of information 3 Refs? 3.1 That really DOES need a reference 3.2 "Shiny White" 3.2.1 Shiny white from own experience 3.3 Effects 3.4 "Shiny White -- really gotta fix this" 3.5 Cleanup

[edit] Neil

The comparison between caffeine and methcathinone is misleading. Methcathinone is nowhere near caffeine and has probably the same intensity of effect as methamphetamine. Also corrected details where I could see differences with experience. Neil (I'll sign up as a user if I do any more editing.) Hope I didn't make much of a mess of the edit. :)

Also backed up from experience there are two forms of the drug. One is less potent without having been cut. Something to do with the manufacturing process having not been completed. If I recall the less potent one is called Cathinone. I think this should be included in the document as well as it explains different perceptions of strength.

Actually, I believe that even methcathinone can come in two forms. NOT Cathinone vs Methcathinone, but 2 forms of methcathinone. The street term was "rocked up" versus "not rocked up". ClintJCL (talk) 01:22, 14 January 2008 (UTC)

See Freebase (chemistry) vs. salt (chemistry). Сасусlе 01:47, 14 January 2008 (UTC)

[edit] Sources of information

The changes were from experience. It will probably be better to back the information up from credible sources such as:

http://www.totse.com/en/drugs/speedy_drugs/93hq0034.html

[edit] Refs?

What? Sodium hypochlorite can be used to make Methcathinone? How?

-ert

NaOCl is an oxidizer. That really doesn't need a reference.--141.154.232.5 14:11, 13 December 2006 (UTC)

It'll go all the way to benzaldehyde. -ert

[edit] That really DOES need a reference

Sodium hypochlorite cannot be used in the manufacture of methcathinone, also potassium permanganate is said to be low-yelding then high-yelding reactant in the same paragraph... The reference [1] shouldn't be trusted since it has been edited as follow :

[editor's note: My reservations about the above post come from the fact that it looks almost exactly like a combination of the permanganate method published by Zhingel et al. in J. Forensic Sci. 36 (1991): 915-20 (this is in the Methcathinone FAQ 2.2, towards the end of the FAQ.) and the hypochlorite method of oxidizing alcohols I've seen in a number of recent organic chemistry laboratory textbooks. The original poster may just have replaced the steps in the permangante method, with those from the hypochlorite method. Of course, this may be exactly how the original poster developed a synthetic protocol that maybe does work.]

Here is another article [2] that could be read trustfully :

Potassium permanganate and potassium dichromate produced methcathinone in high yields. Two significant impurities were found when pseudoephedrine was reacted with potassium permanganate. Oxidation of pseudoephedrine with sodium hypochlorite resulted in the formation of benzaldehyde and N-(phenylmethylene)-methanamine.

--Littlebmx 14:30, 26 September 2007 (UTC)

[edit] "Shiny White"

What is this "shiny white" effect described on the page when they compare methamphetamine to methcathinone?

24.200.159.238 19:53, 1 January 2007 (UTC)

[edit] Shiny white from own experience

Clean and very bright effect. Everything is shining and warm. Addicts describe this as the effect in crystal meth which they are trying to duplicate in subsequent uses.

From [[3]]

 In an article about his son's addiction to methamphetamine, a California writer who has also experimented with the drug put it this way:
 [T]his drug has a unique, horrific quality. In an interview, Stephan Jenkins, the singer in the band Third Eye Blind, said that 
 methamphetamine makes you feel 'bright and shiny.' It also makes you paranoid, incoherent and both destructive and pathetically and 
 relentlessly self-destructive. Then you will do unconscionable things in order to feel bright and shiny again.[23]

Neil

[edit] Effects

It might be worth mentioning that the effects of this chemical, at least the ones listed, are almost identical to benzylpiperazine. Just a thought... Gabethenerd 06:59, 2 May 2007 (UTC)

[edit] "Shiny White -- really gotta fix this"

"Methcathinone's effects differ in various characteristic ways to that of methamphetamine. The effects seem to be of somewhat similar intensity to methamphetamine, differing in the nature of the shiny white effect which characterises the first few methamphetamine uses, and the dopamine and serotonin.effects are quite apparent and also produce a shiny white effect which is quite different to that of methamphetamine and is more localized to the head."

This is absolutely absurd. In no way does this qualify as encyclopedia-worthy content or style. "A shiny white effect which is...more localized to the head." Imagine a doctor coming up to you, saying, "We're prescribing you a stimulant which may be a little different to what you're used to. Along with increased pulse, sleeplessness, anxiety, and damage to the dopaminergic system in the brain, you can also expect A WHITE SHINY FEELING WHICH IS LOCALIZED TO THE HEAD."

No, a doctor wouldn't say that. Nor would a pharmacologist. Or a biologist. Nobody. So, don't say it. 'Cause it's rubbish. Your personal experience DOES NOT go in an encyclopedia. That isn't one of those somewhat stupid rules about encyclopedias, it's one of the sensible ones. And claiming something as an "effect" means a *reproducible effect* (as well as a meaningful one -- after all, what the hell does that even mean, a "shiny white effect"??!?!?). You don't put "engenders shopping" in the list of effects, just because you shopped while on the drug. Sorry. Methcathinone may not be well studied, and you may think you're filling a void in the understanding of the mathcathinone experience with your anecdote, but it's just not appropriate or meaningful. If there was some sort of wide spread anecdotal consensus about SOMETHING MEANINGFUL ("shiny white" is a color, not an effect of a drug!!!!!! the statement conveys nothing to readers, however meaningful it may be to you) then, labeled as such, it might be a good thing to include in an article about a medical topic where there is a lack of clinical info.

And, no, citing the Third Eye Blind guy, and what he said about *methamphetamine*, does not count as a citation for you making an *opposite* claim about *methcathinone*! Creative, I'll give you that, but not legitimate citation.

Someone clean this up, or I'll try to get around to it.

The whole article is a mess. Remember: we want articles ABOUT drugs, not written while incapacitated BY drugs. —Preceding unsigned comment added by 24.5.70.65 (talk) 08:41, 23 September 2007 (UTC)

[edit] Cleanup

I have added some verifiable information about affinities, I have removed the false statement at the top of the article about it having a higher affinity for the serotonin transporter than amphetamines, and I have removed the "shiny white" paragraphs. Subjective stuff like this are better off on somewhere like lycaeum.org or the vaults of erowid.

There is still a whole lot of stuff that needs citing. Woood (talk) 01:07, 20 November 2007 (UTC)