Methylpentynol

From Wikipedia, the free encyclopedia

Methylpentynol
Systematic (IUPAC) name
3-methylpent-1-yn-3-ol
Identifiers
CAS number 77-75-8
ATC code N05CM15
PubChem 6494
Chemical data
Formula C6H10O 
Mol. mass 98.143 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Methylpentynol (Methylparafynol, Dormison, Atemorin) is a hypnotic/sedative with anticonvulsant effects. It was previously used for the treatment of insomnia but has been replaced by newer drugs with better safety profiles.[1][2][3][4]


[edit] References

  1. ^ HIRSH HL, ORSINGER WH. Methylparafynol--a new type hypnotic. Preliminary report on its therapeutic efficacy and toxicity. American Practitioner and Digest of Treatment. 1952 Jan;3(1):23-6.
  2. ^ SCHAFFARZICK RW, BROWN BJ. The anticonvulsant activity and toxicity of methylparafynol (dormison) and some other alcohols. Science. 1952 Dec 12;116(3024):663-5.
  3. ^ HERZ A. A new type of hypnotic; unsaturated tertiary carbinols; experimental studies on therapeutic use of 3-methyl-pentin-ol-3 (methylparafynol). Arzneimittelforschung. 1954 Mar;4(3):198-9.
  4. ^ WEAVER LC, ALEXANDER WM, ABREU BE. Anticonvulsant activity of compounds related to methylparafynol. Archives Internationales de Pharmacodynamie et de Therapie. 1961 Apr 1;131:116-22.