Methylergonovine

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Methylergonovine
Systematic (IUPAC) name
9,10-didehydro-N-[1-(hydroxymethyl)-propyl]-D-lysergamide
Identifiers
CAS number	113-42-8
ATC code	?
PubChem	8226
Chemical data
Formula	C₂₀H₂₅N₃O₂
Mol. mass	339.432 g/mol
SMILES	eMolecules & PubChem
Synonyms	Methylergonovine
Physical data
Melt. point	172 °C (342 °F)
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	Prescription Only Medicine
Routes	?

Methylergonovine, also known as methylergometrine, methylergobasin, and d-lysergic acid 1-butanol amide, is a synthetic analogue of ergonovine, a psychedelic alkaloid found in ergot, and many species of morning glory. It is a member of the ergoline family and chemically similar to LSD, ergine, ergonovine, and lysergic acid. Due to its oxytocic properties, it has a medical use in obstetrics. According to Jonathan Ott, methylergonovine has LSD-like actions above 2 milligrams. Clinical dosages are ten times lower.

[edit] Obstetric Use

Methergine (methylergonovine maleate) is a blood vessel constrictor and smooth muscle agonist most commonly used to prevent or control excessive bleeding following childbirth and spontaneous or elective abortion. It also causes uterine contractions to aid in expulsion of retained products of conception after a missed abortion (miscarriage in which all or part of the fetus remains in the uterus) and to help deliver the placenta after childbirth. It is available as tablets or injection (IM or IV) or in liquid form to be taken orally.

[edit] Side Effects

cholinergic effects such as nausea, vomiting, and diarrhea
cramping
dizziness.

[edit] Contraindications

hypertension
pregnancy

v • d • e Psychedelic lysergamides

AL-LAD • ALD-52 • BU-LAD • CYP-LAD • Diallyllysergamide • DAM-57 • Ergonovine • ETH-LAD • LAE-32 • LSD • LPD-824 • LSM-775 • D-Lysergic acid N-(α-hydroxyethyl)amide • Methylergonovine • MLD-41 • PARGY-LAD • PRO-LAD