Metharbital

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Metharbital
Systematic (IUPAC) name
5,5-diethyl-1-methyl-hexahydropyrimidine-2,4,6-trione
Identifiers
CAS number	50-11-3
ATC code	N03AA30
PubChem	4099
DrugBank	APRD00757
Chemical data
Formula	C9H14N2O3
Mol. mass	198.219 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Metharbital was patented in 1905 by Emil Fischer working for Merck^[1]. It was marketed as Gemonil by Abbott Laboratories. It is a barbiturate anticonvulsant, used in the treatment of epilepsy. It has similar properties to phenobarbital.

[edit] History

• 1952 Gemonil was introduced by Abbott Laboratories.
• 1990 Abbott stopped marketing.

[edit] References

• The Treatment of Epilepsy 2nd Ed by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. ISBN 0-632-06046-8
• The Medical Treatment of Epilepsy by Stanley R Resor. Published by Marcel Dekker (1991). ISBN 0-8247-8549-5.
• The Comparative Toxicogenomics Database: Metharbital

1. ^ US Patent 782742

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