Metergoline

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Metergoline
IUPAC name benzyl ((6aR,9S,10aR)-4,7-dimethyl- 4,6,6a,7,8,9,10,10a-octahydroindolo- [4,3-fg]quinolin-9-yl)methylcarbamate
Identifiers
CAS number [17692-51-2]
PubChem 28693
MeSH Metergoline
SMILES Cn1cc(C[C@]2([H])[C@]3([H])C[C@@H] (CN([H])C(OCc4ccccc4)=O)CN2C)c5c3cccc51
Properties
Molecular formula C25H29N3O2
Molar mass 403.517 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Metergoline is a synthetic compound, that acts on subsets of both 5-HT receptors and dopamine receptors. Metergoline has been reported to be a 5-HT1D receptor agonist.[1]

[edit] References

  1. ^ Miller KJ, King A, Demchyshyn L, Niznik H, Teitler M (1992). "Agonist activity of sumatriptan and metergoline at the human 5-HT1D beta receptor: further evidence for a role of the 5-HT1D receptor in the action of sumatriptan". Eur. J. Pharmacol. 227 (1): 99–102. PMID 1330643. 

[edit] External links


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