Metelimumab

From Wikipedia, the free encyclopedia

Metelimumab?
Therapeutic monoclonal antibody
Source Human
Target CAT-192
Identifiers
CAS number  ?
ATC code  ?
PubChem  ?
Chemical data
Formula  ?
Mol. mass  ?
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Metelimumab (CAT-192) is a human IgG4 monoclonal antibody that neutralizes TGF-beta1 which has been chosen for further development for the treatment of diffuse cutaneous systemic sclerosis. In clinical studies, metelimumab was shown to be generally safe and well tolerated, with a long half-life, and has reached phase I/II development.[1]

[edit] References

  1. ^ Journals on the Web