Metacam

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It has been suggested that this article or section be merged into Meloxicam. (Discuss)


Metacam
Systematic (IUPAC) name
(8E)-8-[hydroxy-[(5-methyl-1,3-thiazol-2-yl)amino] methylidene]-9-methyl-10,10-dioxo-10λ⁶-thia-9- azabicyclo[4.4.0]deca-1,3,5-trien-7-one
Identifiers
CAS number	71125-38-7
ATC code	M01AC06
PubChem	5281106
DrugBank	APRD00529
Chemical data
Formula	C₁₄H₁₃N₃O₄S₂
Mol. mass	351.403 g/mol
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Protein binding	99.4%
Metabolism	Hepatic
Half life	15 to 20 hours
Excretion	Urine & Faeces equally
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	Oral and injectable

Metacam is the brand name for the anti-inflammatory drug Meloxicam intended for veterinary use. It is marketed by Boehringer-Ingelheim Vetmedica.

Metacam is classified as an NSAID (Non-Steroidal Anti-Inflammatory) and in the US is indicated for management of pain and inflammation associated with osteoarthritis in Dogs (FDA.gov). In Europe, where the product has been available since the early 1990s, it is also prescribed and licensed for other anti-inflammatory benefits including relief from both acute and chronic pain in dogs and cats. For many years, Metacam has been licensed for use in dogs (injectable and oral forms), and in cats for use in the injectable form.

In June 2007, a new oral version of Metacam was licensed in Europe for the long-term relief of pain in cats.

Metacam is available as an injectable solution, an oral suspension (liquid), and as a palatable tablet. It has a similar side profile in animals as humans, but principal side effects are gastrointestinal irritation (vomiting, diarrhea and ulceration). Rarer but important side effects include liver and kidney toxicity.

Metacam Oral Suspension is labeled for Dogs in the US and has a Dog and Cat label in the EU. A veterinarian should be consulted and can prescribe Metacam to your animal if they feel it is the best medicine for their pain.