MESDC2

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Mesoderm development candidate 2
PDB rendering based on 2i9s.
Available structures: 2i9s
Identifiers
Symbol(s) MESDC2; BOCA; KIAA0081; MESD
External IDs OMIM: 607783 MGI1891421 HomoloGene11347
Orthologs
Human Mouse
Entrez 23184 67943
Ensembl ENSG00000117899 ENSMUSG00000038503
Uniprot Q14696 Q8CCX7
Refseq NM_015154 (mRNA)
NP_055969 (protein)
NM_023403 (mRNA)
NP_075892 (protein)
Location Chr 15: 79.03 - 79.07 Mb Chr 7: 83.77 - 83.78 Mb
Pubmed search [1] [2]

Mesoderm development candidate 2, also known as MESDC2, is a human gene.[1]


[edit] References

[edit] Further reading

  • Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99-106. PMID 12168954. 
  • Nagase T, Miyajima N, Tanaka A, et al. (1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 2 (1): 37-43. PMID 7788527. 
  • Scanlan MJ, Gordan JD, Williamson B, et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma.". Int. J. Cancer 83 (4): 456-64. PMID 10508479. 
  • Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491-6. PMID 10737800. 
  • Wines ME, Lee L, Katari MS, et al. (2001). "Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis.". Genomics 72 (1): 88-98. doi:10.1006/geno.2000.6466. PMID 11247670. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Hsieh JC, Lee L, Zhang L, et al. (2003). "Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity.". Cell 112 (3): 355-67. PMID 12581525. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Veltman IM, Vreede LA, Cheng J, et al. (2005). "Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25).". Hum. Mol. Genet. 14 (14): 1955-63. doi:10.1093/hmg/ddi200. PMID 15917269. 
  • Li Y, Lu W, He X, Bu G (2006). "Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd.". FEBS Lett. 580 (22): 5423-8. doi:10.1016/j.febslet.2006.09.011. PMID 16989816.