MESDC2
From Wikipedia, the free encyclopedia
Mesoderm development candidate 2
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PDB rendering based on 2i9s. | ||||||||||||||
Available structures: 2i9s | ||||||||||||||
Identifiers | ||||||||||||||
Symbol(s) | MESDC2; BOCA; KIAA0081; MESD | |||||||||||||
External IDs | OMIM: 607783 MGI: 1891421 HomoloGene: 11347 | |||||||||||||
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Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 23184 | 67943 | ||||||||||||
Ensembl | ENSG00000117899 | ENSMUSG00000038503 | ||||||||||||
Uniprot | Q14696 | Q8CCX7 | ||||||||||||
Refseq | NM_015154 (mRNA) NP_055969 (protein) |
NM_023403 (mRNA) NP_075892 (protein) |
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Location | Chr 15: 79.03 - 79.07 Mb | Chr 7: 83.77 - 83.78 Mb | ||||||||||||
Pubmed search | [1] | [2] |
Mesoderm development candidate 2, also known as MESDC2, is a human gene.[1]
[edit] References
[edit] Further reading
- Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99-106. PMID 12168954.
- Nagase T, Miyajima N, Tanaka A, et al. (1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 2 (1): 37-43. PMID 7788527.
- Scanlan MJ, Gordan JD, Williamson B, et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma.". Int. J. Cancer 83 (4): 456-64. PMID 10508479.
- Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491-6. PMID 10737800.
- Wines ME, Lee L, Katari MS, et al. (2001). "Identification of mesoderm development (mesd) candidate genes by comparative mapping and genome sequence analysis.". Genomics 72 (1): 88-98. doi: . PMID 11247670.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi: . PMID 12477932.
- Hsieh JC, Lee L, Zhang L, et al. (2003). "Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity.". Cell 112 (3): 355-67. PMID 12581525.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi: . PMID 12975309.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi: . PMID 15489334.
- Veltman IM, Vreede LA, Cheng J, et al. (2005). "Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25).". Hum. Mol. Genet. 14 (14): 1955-63. doi: . PMID 15917269.
- Li Y, Lu W, He X, Bu G (2006). "Modulation of LRP6-mediated Wnt signaling by molecular chaperone Mesd.". FEBS Lett. 580 (22): 5423-8. doi: . PMID 16989816.