Melamine cyanurate

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Melamine cyanurate is a salt formed between melamine and cyanuric acid. It has recently come to light that melamine cyanurate may be found in Chinese gluten, which has been linked to the United States food supply.[1]

Melamine cyanurate[2]
IUPAC name 1,3,5-Triazine-2,4,6(1H,3H,5H)

-trione, compd. with 1,3,5- triazine-2,4,6-triamine (1:1)

Other names Melamine isocyanurate
Melamine-cyanuric acid compound
Identifiers
CAS number [37640-57-6
(Fmr. 70371-20-9)]
PubChem 93198
MeSH cyanurate melamine cyanurate
SMILES n1c(N)nc(N)nc1N.N1C(=O)NC(=O)NC1=O
Properties
Molecular formula C6H9N9O3
(C3H6N6.C3H3N3O3)
Molar mass 255.194160 g/mol
Solubility in water  ? g/l (20°C)
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Contents

[edit] Synthesis

Melamine and cyanuric acid easily form hydrogen bonds between their two aromatic rings.

[edit] Uses

Melamine cyanurate is commonly used as a fire retardant. [3]

[edit] Regulation

[edit] Toxicity

It has been considered to be more toxic than either melamine or cyanuric acid alone.[4]

LD50 in rats and mice (ingested):

  • 4.1 g/kg - Melamine Cyanurate
  • 6.0 g/kg - Melamine
  • 7.7 g/kg - Cyanuric acid

A toxicology study conducted after recent pet food recalls concluded that the combination of melamine and cyanuric acid in diet does lead to acute renal failure in cats.[5]

[edit] See also

[edit] References

  1. ^ "Hogs That Ate Melamine Not Fit For Humans, FDA Rules" Boston Globe. April 27, 2007.
  2. ^ EPA: Substance :
  3. ^ Chemical Search Engine
  4. ^ A.A. Babayan, A.V.Aleksandryan, "Toxicological characteristics of melamine cyanurate, melamine and cyanuric acid", Zhurnal Eksperimental'noi i Klinicheskoi Meditsiny, Vol.25, 345-9 (1985). Original article in Russian.
  5. ^ Puschner et al. (November 2007). Assessment of melamine and cyanuric acid toxicity in cats. Journal of Veterinary Diagnostic Investigation. Retrieved on 2007-11-16.