Portal:Medicine/Did you know

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  • ...the brain itself is not sensitive to pain, because it lacks pain-sensitive nerve fibers? Several areas of the head can hurt, including a network of nerves which extends over the scalp and certain nerves in the face, mouth, and throat.
  • ...that irritable bowel syndrome (IBS) may sometimes have an acute onset and develop after an infectious illness, and that this "Post infectious IBS" (IBS-PI) is drawing much clinical investigation?

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  • ...the Rules of surgery include "Don't mess with the pancreas", "Don't stand when you can sit, Don't sit when you can lie down, Don't lie down when you can sleep" and "See a donut, eat a donut"?



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  • ...infantile pyloric stenosis is a not uncommon pediatric condition where there is a congenital narrowing of the pylorus (the opening at the lower end of the stomach)? Babies with this condition usually present within the first few weeks (usually between 2nd and 3rd) of life with poor feeding, weight loss and progressively worsening vomiting leading ultimately to projectile non-bilious vomiting.
  • ...the Cotard delusion (or Cotard's syndrome, le délire de négation) is a rare disorder in which a person holds a delusional belief that he is dead, does not exist, is putrefying or has lost his blood or internal organs?



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  • ...that during the "Age of Heroic Medicine" (1780-1850), educated professional physicians aggressively practiced "heroic medicine", including bloodletting (venesection), intestinal purging (calomel), vomiting (tartar emetic), profuse sweating (diaphoretics) and blistering? These medical treatments were well-intentioned, and often well-accepted by the medical community, but were actually harmful to the patient.



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  • ...Oral rehydration therapy (ORT) is a simple, cheap, and effective treatment for diarrhea-related dehydration? It is used around the world, but is most important in the Third World, where it saves millions of children from diarrhea—still their leading cause of death. According to The Lancet (1978), ORT is "potentially the most important medical discovery of the 20th century".
  • ...the term "dengue" is a Spanish attempt at the Swahili phrase "ki denga pepo", meaning "cramp- like seizure caused by an evil spirit"? "Beriberi" on the other hand, originates from the Sinhalese (Sri Lankan) language meaning "I cannot, I cannot".



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  • ...erythema infectiosum is the fifth disease of childhood, also known as slapped cheek syndrome, slap face or slapped face? It's caused by parvovirus B19, and usually follows a mild course.
  • ...Reye's syndrome is a potentially fatal disease that causes detrimental effects mainly to the brain and liver? The cause of Reye's syndrome remains unknown; however, a link was found with the use of aspirin or other salicylates in children and adolescents who have a viral infection such as influenza, chicken pox or the common cold. The potentially increased risk of contracting Reye's syndrome is one of the main reasons that aspirin is not recommended for use in people under the age of 16.



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  • ...the symptoms of Alzheimer's disease as a distinct entity were first identified by Emil Kraepelin, and the characteristic neuropathology was first observed by Alois Alzheimer, a German psychiatrist, in 1906? In this sense, the disease was co-discovered by Kraepelin and Alzheimer, who worked in Kraepelin's laboratory. Because of the overwhelming importance Kraepelin attached to finding the neuropathological basis of psychiatric disorders, Kraepelin made the generous decision that the disease would bear Alzheimer's name.



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  • The therapeutic index of a medication is a comparison of the amount that causes the therapeutic effect to the amount that causes toxic effects. Quantitatively, it is the ratio of the dose required to produce the desired therapeutic effect and the toxic dose. A commonly used measure of therapeutic index is the effective dose of a drug for 50% of the population (ED50) divided by the lethal dose for 50% of the population (LD50).

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