Medial globus pallidus

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Brain: Medial globus pallidus
Globus pallidus labeled at bottom right.
DA-loops in PD
NeuroNames hier-215

The medial globus pallidus (or internal, GPi) is one of the output nuclei of the basal ganglia (the other being the substantia nigra pars reticulata). The GABA-containing neurons send their axons to specific nuclei of the dorsal thalamus (VA and VL), to the centremedian complex and to the pedunculopontine complex.[1][2]

The efferent bundle is constituted first of the ansa and fasciculus lenticularis, then crosses the internal capsule as the Edinger's comb system then arrives at the laterosuperior corner of the subthalamic nucleus and constitutes the Forel's field H2, then H, and suddenly changes its direction to form H1 that goes to the inferior part of the thalamus. The distribution of axonal islands is widespread in the lateral region of the thalamus. The innervation of the central region is done by collaterals.[3]

[edit] References

  1. ^ Nauta, W.J.H. and Mehler, W.R. (1966) Projections of the lentiform nucleus in the monkey. Brain Res. 1: 3-42
  2. ^ Percheron, G., François, C., Talbi, B., Yelnik, J., Fenelon, G. (1996) The primate motor thalamus. Brain Res. Rev. 22: 93-181
  3. ^ Arrechi-Bouchhioua, P., Yelnik, K., François, C..,Percheron. G., Tandé, D. (1997) Three-dimensional morphology and distribution of pallidal axons projecting to both the lateral region of the thalamus and the central complex in primates. Brain Res. 754: 311-314