MED25

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Mediator of RNA polymerase II transcription, subunit 25 homolog (S. cerevisiae)
Identifiers
Symbol(s) MED25; P78; ACID1; ARC92; DKFZp434K0512; MGC70671; TCBAP0758
External IDs MGI: 1922863 HomoloGene: 12614
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 81857 75613
Ensembl ENSG00000104973 ENSMUSG00000002968
Refseq NM_030973 (mRNA)
NP_112235 (protein)		 NM_029365 (mRNA)
NP_083641 (protein)
Location Chr 19: 55.01 - 55.03 Mb Chr 7: 44.75 - 44.76 Mb
Pubmed search [1] [2]

Mediator of RNA polymerase II transcription, subunit 25 homolog (S. cerevisiae), also known as MED25, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: MED25 mediator of RNA polymerase II transcription, subunit 25 homolog (S. cerevisiae).

[edit] Further reading

  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174. 
  • Näär AM, Beaurang PA, Zhou S, et al. (1999). "Composite co-activator ARC mediates chromatin-directed transcriptional activation.". Nature 398 (6730): 828–32. doi:10.1038/19789. PMID 10235267. 
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166. 
  • Wang C, McCarty IM, Balazs L, et al. (2002). "A prostate-derived cDNA that is mapped to human chromosome 19 encodes a novel protein.". Biochem. Biophys. Res. Commun. 296 (2): 281–7. PMID 12163014. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Sato S, Tomomori-Sato C, Banks CA, et al. (2004). "A mammalian homolog of Drosophila melanogaster transcriptional coactivator intersex is a subunit of the mammalian Mediator complex.". J. Biol. Chem. 278 (50): 49671–4. doi:10.1074/jbc.C300444200. PMID 14576168. 
  • Tomomori-Sato C, Sato S, Parmely TJ, et al. (2004). "A mammalian mediator subunit that shares properties with Saccharomyces cerevisiae mediator subunit Cse2.". J. Biol. Chem. 279 (7): 5846–51. doi:10.1074/jbc.M312523200. PMID 14638676. 
  • Mittler G, Stühler T, Santolin L, et al. (2004). "A novel docking site on Mediator is critical for activation by VP16 in mammalian cells.". EMBO J. 22 (24): 6494–504. doi:10.1093/emboj/cdg619. PMID 14657022. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Yang F, DeBeaumont R, Zhou S, Näär AM (2004). "The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2339–44. PMID 14983011. 
  • Sato S, Tomomori-Sato C, Parmely TJ, et al. (2004). "A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology.". Mol. Cell 14 (5): 685–91. doi:10.1016/j.molcel.2004.05.006. PMID 15175163. 
  • Zhang X, Krutchinsky A, Fukuda A, et al. (2005). "MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription.". Mol. Cell 19 (1): 89–100. doi:10.1016/j.molcel.2005.05.015. PMID 15989967. 
  • Lee HK, Park UH, Kim EJ, Um SJ (2007). "MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation.". EMBO J. 26 (15): 3545–57. doi:10.1038/sj.emboj.7601797. PMID 17641689. 
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