MBNL2

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Muscleblind-like 2 (Drosophila)
Identifiers
Symbol(s) MBNL2; DKFZp781H1296; MBLL; MBLL39; MGC120625; MGC120626; MGC120628; PRO2032
External IDs OMIM: 607327 MGI: 2145597 HomoloGene: 76766
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10150 105559
Ensembl ENSG00000139793 ENSMUSG00000022139
Refseq NM_144778 (mRNA)
NP_659002 (protein)		 NM_175341 (mRNA)
NP_780550 (protein)
Location Chr 13: 96.67 - 96.84 Mb Chr 14: 119.41 - 119.57 Mb
Pubmed search [1] [2]

Muscleblind-like 2 (Drosophila), also known as MBNL2, is a human gene.[1]

This gene encodes a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein. Drosophila muscleblind is a gene required for photoreceptor differentiation. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.[1]

[edit] References

  1. ^ a b Entrez Gene: MBNL2 muscleblind-like 2 (Drosophila).

[edit] Further reading

  • Adereth Y, Dammai V, Kose N, et al. (2006). "RNA-dependent integrin alpha3 protein localization regulated by the Muscleblind-like protein MLP1.". Nat. Cell Biol. 7 (12): 1240-7. doi:10.1038/ncb1335. PMID 16273094. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ho TH, Charlet-B N, Poulos MG, et al. (2005). "Muscleblind proteins regulate alternative splicing.". EMBO J. 23 (15): 3103-12. doi:10.1038/sj.emboj.7600300. PMID 15257297. 
  • Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522-8. doi:10.1038/nature02379. PMID 15057823. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Christian SL, McDonough J, Liu Cy CY, et al. (2002). "An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia.". Genomics 79 (5): 635-56. doi:10.1006/geno.2002.6765. PMID 11991713. 
  • Fardaei M, Rogers MT, Thorpe HM, et al. (2002). "Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells.". Hum. Mol. Genet. 11 (7): 805-14. PMID 11929853. 
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