MARCH5

From Wikipedia, the free encyclopedia

Membrane-associated ring finger (C3HC4) 5

Identifiers

MARCH5; FLJ20445; MARCH-V; RNF153

External IDs

OMIM: 610637 MGI: 1915207 HomoloGene: 9862

Gene ontology
Molecular Function:	• protein binding • zinc ion binding • metal ion binding
Cellular Component:	• membrane • integral to membrane • outer membrane
Biological Process:	• ubiquitin cycle

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_017824 (mRNA)
NP_060294 (protein)

XM_974595 (mRNA)
XP_979689 (protein)

Location

Chr 10: 94.04 - 94.1 Mb

Chr 19: 37.27 - 37.29 Mb

Pubmed search

[1]

[2]

Membrane-associated ring finger (C3HC4) 5, also known as MARCH5, is a human gene.^[1]

[edit] References

^ Entrez Gene: MARCH5 membrane-associated ring finger (C3HC4) 5.

[edit] Further reading

Karbowski M, Neutzner A, Youle RJ (2007). "The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division.". J. Cell Biol. 178 (1): 71-84. doi:10.1083/jcb.200611064. PMID 17606867.
Nakamura N, Kimura Y, Tokuda M, et al. (2006). "MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology.". EMBO Rep. 7 (10): 1019-22. doi:10.1038/sj.embor.7400790. PMID 16936636.
Yonashiro R, Ishido S, Kyo S, et al. (2006). "A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics.". EMBO J. 25 (15): 3618-26. doi:10.1038/sj.emboj.7601249. PMID 16874301.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375-81. doi:10.1038/nature02462. PMID 15164054.
Bartee E, Mansouri M, Hovey Nerenberg BT, et al. (2004). "Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.". J. Virol. 78 (3): 1109-20. PMID 14722266.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.