MAP1S

From Wikipedia, the free encyclopedia

Microtubule-associated protein 1S

Identifiers

MAP1S; BPY2IP1; C19orf5; FLJ10669; MAP8; MGC133087; VCY2IP-1; VCY2IP1

External IDs

OMIM: 607573 MGI: 2443304 HomoloGene: 10047

Gene ontology
Molecular Function:	• DNA binding • deoxyribonuclease activity • protein binding • microtubule binding • beta-tubulin binding • actin filament binding
Cellular Component:	• nucleus • cytosol • microtubule • dendrite • cell soma • perinuclear region of cytoplasm
Biological Process:	• microtubule bundle formation • apoptosis • nervous system development • brain development • mitochondrion transport along microtubule • neurite morphogenesis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018174 (mRNA)
NP_060644 (protein)

NM_173013 (mRNA)
NP_766601 (protein)

Location

Chr 19: 17.69 - 17.71 Mb

Chr 8: 73.83 - 73.85 Mb

Pubmed search

[1]

[2]

Microtubule-associated protein 1S, also known as MAP1S, is a human gene.^[1]

[edit] References

^ Entrez Gene: MAP1S microtubule-associated protein 1S.

[edit] Further reading

Liu L, McKeehan WL (2002). "Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity.". Genomics 79 (1): 124-36. doi:10.1006/geno.2001.6679. PMID 11827465.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Liu L, Amy V, Liu G, McKeehan WL (2003). "Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells.". In Vitro Cell. Dev. Biol. Anim. 38 (10): 582-94. PMID 12762840.
Wong EY, Tse JY, Yao KM, et al. (2004). "Identification and characterization of human VCY2-interacting protein: VCY2IP-1, a microtubule-associated protein-like protein.". Biol. Reprod. 70 (3): 775-84. doi:10.1095/biolreprod.103.018531. PMID 14627543.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Dallol A, Agathanggelou A, Fenton SL, et al. (2004). "RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics.". Cancer Res. 64 (12): 4112-6. doi:10.1158/0008-5472.CAN-04-0267. PMID 15205320.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Orbán-Németh Z, Simader H, Badurek S, et al. (2005). "Microtubule-associated protein 1S, a short and ubiquitously expressed member of the microtubule-associated protein 1 family.". J. Biol. Chem. 280 (3): 2257-65. doi:10.1074/jbc.M408984200. PMID 15528209.
Liu L, Vo A, McKeehan WL (2005). "Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5.". Cancer Res. 65 (5): 1830-8. doi:10.1158/0008-5472.CAN-04-3896. PMID 15753381.
Liu L, Vo A, Liu G, McKeehan WL (2005). "Putative tumor suppressor RASSF1 interactive protein and cell death inducer C19ORF5 is a DNA binding protein.". Biochem. Biophys. Res. Commun. 332 (3): 670-6. doi:10.1016/j.bbrc.2005.05.006. PMID 15907802.
Ding J, Valle A, Allen E, et al. (2006). "Microtubule-associated protein 8 contains two microtubule binding sites.". Biochem. Biophys. Res. Commun. 339 (1): 172-9. doi:10.1016/j.bbrc.2005.10.199. PMID 16297881.
Foster LJ, Rudich A, Talior I, et al. (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).". J. Proteome Res. 5 (1): 64-75. doi:10.1021/pr0502626. PMID 16396496.