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Portuguese royalty
House of Aviz-Beja
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| Manuel I |
| Children include |
| Miguel da Paz, Prince of Portugal and of Asturias |
| João, Prince of Portugal (future John III) |
| Isabella, Holy Roman Empress |
| Infanta Beatriz, Duchess of Savoy |
| Infante Luís, Duke of Beja |
| Infante Fernando, Duke of Guarda and Trancoso |
| Cardinal-Infante Afonso |
| Henry I |
| Infante Duarte, Duke of Guimarães |
| Infanta Maria, Lady of Viseu |
| Grandchildren include |
| Philip II of Spain and I of Portugal) |
| Anthony I (illegitimate) |
| Infanta Maria of Guimarães, Duchess of Parma and Piacenza |
| Infanta Catarina of Guimarães, Duchess of Braganza |
| Great-Grandchildren include |
| Teodósio II, Duke of Braganza |
| Ranuccio I Farnese of Parma |
| Great-Great-Grandchildren include |
| John II, Duke of Braganza (future John IV) |
| John III |
| Children include |
| Maria Manuela, Princess of Portugal and of Asturias |
| João Manuel, Prince of Portugal |
| Grandchildren include |
| Sebastião, Prince of Portugal (future Sebastian I) |
| Carlos, Prince of Asturias |
| Sebastian |
| Henry |
| Anthony (disputed king) |
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Infante Manuel, Prince of Portugal was the Prince of Portugal from 1535 to his death in 1537. He was born in 1531, son of king John III of Portugal and Catherine of Austria.
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