Mannosyl-3-phosphoglycerate synthase

From Wikipedia, the free encyclopedia

In enzymology, a mannosyl-3-phosphoglycerate synthase (EC 2.4.1.217) is an enzyme that catalyzes the chemical reaction

GDP-mannose + 3-phospho-D-glycerate GDP + 2-(alpha-D-mannosyl)-3-phosphoglycerate

Thus, the two substrates of this enzyme are GDP-mannose and 3-phospho-D-glycerate, whereas its two products are GDP and 2-(alpha-D-mannosyl)-3-phosphoglycerate.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:3-phosphoglycerate 3-alpha-D-mannosyltransferase. This enzyme is also called MPG synthase.

[edit] References

• IUBMB entry for 2.4.1.217
• BRENDA references for 2.4.1.217 (Recommended.)
• PubMed references for 2.4.1.217
• PubMed Central references for 2.4.1.217
• Google Scholar references for 2.4.1.217
• Empadinhas N, Marugg JD, Borges N, Santos H, da Costa MS (2001). "Pathway for the synthesis of mannosylglycerate in the hyperthermophilic archaeon Pyrococcus horikoshii. Biochemical and genetic characterization of key enzymes". J. Biol. Chem. 276: 43580–8. doi:10.1074/jbc.M108054200. PMID 11562374. 

[edit] External links

The CAS registry number for this enzyme class is 393512-63-5.

• IUBMB entry for 2.4.1.217

• KEGG entry for 2.4.1.217

• BRENDA entry for 2.4.1.217

• NiceZyme view of 2.4.1.217

• EC2PDB: PDB structures for 2.4.1.217

• PRIAM entry for 2.4.1.217

• PUMA2 entry for 2.4.1.217

• IntEnz: Integrated Enzyme entry for 2.4.1.217

• MetaCyc entry for 2.4.1.217

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050504: mannosyl-3-phosphoglycerate synthase

• AMIGO entry for GO code 0050504: mannosyl-3-phosphoglycerate synthase